Search for dissertations about: "mucus layer"
Showing result 21 - 25 of 44 swedish dissertations containing the words mucus layer.
-
21. Molecular associations and transport properties of amphiphiles and gastrointestinal mucin in aqueous solution
Abstract : An effective uptake/absorption of drug formulations involve many processes; one being the transport of the active molecule through the mucus layer. The mucus layer is a complex mixture of biological molecules. Among them, mucin is the molecule that mainly provides the gel properties of the layer. READ MORE
-
22. Characterization of secreted Giardia intestinalis cysteine proteases
Abstract : Giardia intestinalis, the causative agent of the diarrheal disease giardiasis, is a protozoan parasite that colonizes the upper small intestine of mammals, including humans. It can be divided into eight genotypes or assemblages (A through H) and only assemblage A and B are infective to humans. READ MORE
-
23. Diet and inflammation : the role of nitrate and conjugated linoleic acid
Abstract : A diet rich in vegetables and unsaturated fatty acids is associated with a lower risk of major diseases including cardiovascular disease, type 2 diabetes and chronic inflammation. Yet, despite extensive research, the active component(s) responsible for these effects has not been pinpointed and studies with single nutrients have been largely unsuccessful. READ MORE
-
24. DissolvIt : development and validation of a new in vitro dissolution apparatus for dry powder aerosols
Abstract : Today there are no recommended dissolution methods for use in the development of new inhalable drugs. In the absence of such tailored methods, standard dissolution test methods from oral- or skin administration routes are used instead. Such methods are obviously not designed to resemble the lung environment. READ MORE
-
25. Intestinal permeability : a parameter of mucosal dysfunction
Abstract : The gastrointestinal tract has two opposing functions; to absorb nutrients and electrolytes, and to act as a barrier towards hazardous and non-nutritional substances. In the present thesis the barrier function of the gastrointestinal tract was studied in animal models in vivo, in situ and in vitro. READ MORE