Search for dissertations about: "multi target drug design"
Showing result 1 - 5 of 12 swedish dissertations containing the words multi target drug design.
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1. Sequential Decision-Making for Drug Design: Towards closed-loop drug design
Abstract : Drug design is a process of trial and error to design molecules with a desired response toward a biological target, with the ultimate goal of finding a new medication. It is estimated to be up to 10^{60} molecules that are of potential interest as drugs, making it a difficult problem to find suitable molecules. READ MORE
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2. Structure-based Virtual Screening for Ligands of G Protein-coupled Receptors : Design of Allosteric and Dual-Target Modulators
Abstract : G protein-coupled receptors (GPCRs) are integral membrane proteins responsible for signal transduction of extracellular stimuli into the cell. Because of their widespread distribution throughout the human body and important roles in physiological processes, GPCRs are prominent drug targets and approximately 34% of all approved drugs interact with members of this superfamily. READ MORE
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3. Towards a functioning retail health market : Evaluating the integrated Community Case Management Intervention for Pediatric Febrile Illness in Drug Shops in Rural South Western Uganda
Abstract : Objectives: This thesis examined the health systems effects of implementing the integrated Community Case Management (iCCM) intervention for paediatric febrile illnesses in a retail health market in South Western Uganda. More specifically, it evaluated drug seller interpretation of malaria Rapid Diagnostics Test (RDT) results (study I), adherence to iCCM guidelines (study II) and the intervention effect on households’ perceived quality of drug seller fever care and care-seeking choice. READ MORE
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4. Drug use at licensed premises : prevalence and prevention
Abstract : Background: There are a number of public health concerns related to the use of illicit drugs such as violence, injuries, unprotected sex, and drug dependence. Particularly, there is a strong need to reach adolescents and young adults with drug prevention programs. READ MORE
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5. Extracellular matrix mimetic multi-functional scaffolds for tissue engineering and biomedical applications
Abstract : Regeneration of functional tissues or complex organs via the combination of viable cells, biomimetic scaffolds, morphogenic factors, and external biophysical cues are the principle aims of Tissue Engineering (TE). TE relies on the use of artificial 3D scaffolds that can mimic the microenvironment of native tissue to harness the regenerative potential of cells. READ MORE