Search for dissertations about: "multicenter"

Showing result 1 - 5 of 153 swedish dissertations containing the word multicenter.

  1. 1. Impact of disease and treatment on body weight and eating in patients with head and neck cancer : experiences from a multicenter study

    Author : Sandra Ottosson; Göran Laurell; Cecilia Olsson; Björn Zackrisson; Elisabeth Kjellén; Antti Mäkitie; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Head and neck cancer; weight loss; body mass index; tube feeding; radiation therapy; survival; treated volume; swallowing dysfunction; patient experience.; oto-rhino-laryngologi; Oto-Rhino-Laryngology;

    Abstract : Background Nutritional deterioration in patients with head and neck cancer (HNC) has a multifactorial etiology mainly associated with tumor and treatment related factors. The objective of the present thesis was to investigate the impact of the disease and treatment on body weight and eating in patients with HNC treated with radiation therapy (RT) as the single modality treatment or as preoperative RT by analyzing body weight and body mass index (BMI) over time, predictive factors for weight loss and BMI, weight loss and BMI as prognostic factors for survival, and by studying the patients’ own experience of food and eating. READ MORE

  2. 2. Surgical and neurological adverse effects of epilepsy surgery

    Author : Johan Bjellvi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epilepsy surgery; invasive electrode procedures; intracranial EEG; complications; adverse events; risk; seizure worsening; multicenter study; register study; SNESUR;

    Abstract : The aim of this thesis was to study surgical and neurological complications of preoperative invasive investigations and epilepsy surgery procedures (Papers I-II) and seizure worsening after epilepsy surgery (Paper III). A further aim was to improve reporting of adverse effects related to invasive investigations and epilepsy surgery by proposing and evaluating an evidence-based protocol for monitoring complications (Paper IV). READ MORE

  3. 3. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment

    Author : Elena Lundberg; Berit Kriström; Kerstin Albertsson-Wikland; Roland Pfäffle; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gain in height; puberty; IGHD; non-GHD; IGF-I; bioavailability;

    Abstract : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. READ MORE

  4. 4. Tools for Outcome-informed management of mental illness : Psychometric properties of instruments of the Swedish clinical multicenter Quality Star cohort

    Author : Bo Ivarsson; Torsten Norlander; Lars Jacobsson; Karlstads universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Consumer satisfaction; Quality of Life; Perceived distress; Severe mental illness; Schizophrenia; Social function; Global Assessment of Functioning; MANSA; Gender; Brukartillfredsställelse; Livskvalitet; Upplevda besvär; Allvaligt psykisk störning; Schizofreni; Social funktion; Global skattning av psykosocial funktion; MANSA; Gender; Psychology with an emphasis on medical psychology; Psykologi inr. medicinsk psykologi;

    Abstract : The purpose of this thesis was to investigate the psychometric properties of three global user subjective measures of the ”The Quality Star” clinical review model: Consumer Satisfaction Scale, Global Quality of Life scale, and Perceived Global Distress scale. The mental health implementation context of this review model emphasizes the client as an agent of change, taking part in shared decision making in an empowered role as collaborative partner to the professional clinicians. READ MORE

  5. 5. The changing path of inguinal hernia surgery

    Author : Fritz H Berndsen; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; traumatology; Surgery; spermatic cord; recurrence rate; complications; bilaterality; mesh; laparoscopy; randomised multicenter trial; Inguinal hernia; groin hernia; Kirurgi; ortopedi; traumatologi;

    Abstract : Inguinal hernia repair is the most common operation in general surgery and the main challenge has been to lower the recurrence rate. With the introduction of endoscopic repair in the beginning of the 1990´s, the demand for randomised controlled studies has increased resulting in a growing interest in this surgical field. READ MORE