Search for dissertations about: "multiple cancers"

Showing result 16 - 20 of 123 swedish dissertations containing the words multiple cancers.

  1. 16. Colonoscopic surveillance in familial colorectal cancer

    Author : Anna Forsberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : familial;

    Abstract : Colorectal cancer (CRC) is a disease with a high and rising incidence in the industrialized countries. It is the third leading cause of death among cancers in Sweden and the forth worldwide. Important etiological factors are both environmental and lifestyle as well as heritable factors. READ MORE

  2. 17. Familial risks for cancer with reference to lung cancer

    Author : Xinjun Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Familial cancer; population-based; hereditary factors; familial risk; lung neoplasms.;

    Abstract : Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a basis for clinical decisions and counseling, as well as guiding the identification of cancer-related genes. READ MORE

  3. 18. Cancer Genomics - Molecular Analysis of Epithelial Cells

    Author : Anna C. Gustafsson; KTH; []
    Keywords : DNA microarray; Pyrosequencing;

    Abstract : Cancer is a disease involving multiple causal andsymptomatic genetic changes, collectively reflecting theselective pressures that occur during tumor development.Epithelial cancers are by far the most common type of cancerworldwide and investigation of the alterations associated withepithelial carcinogenesis will ultimately lead to improvementsin diagnosis, prognosis, prevention and treatment of thedisease. READ MORE

  4. 19. Computational studies of mutational sequence signatures in cancer genomes

    Author : Markus Lindberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Genomcis; Mutational signatures; Ultraviolet light; Multifocal tumors;

    Abstract : Cancer typically forms when mutational processes modify key cancer driver genes, resulting in positive selection and tumor growth. As such, mutational processes are at the core of the disease. Trinucleotide mutational signatures have emerged in the last decade as essential tools for analysis of mutational processes. READ MORE

  5. 20. Chromatin and transcriptome-based integrative approaches to profile functional long noncoding RNAs - A computational approach

    Author : Santhilal Subhash; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Computational biology; Long noncoding RNAs; Chromatin; S-phase; Cell cycle; sperm; Epigenetics; Histone; cancer; oncogene; Tumor suppressor; DNA methylation; Histone modifications; Chromatin remodelers; lncRNAs; lincRNAs;

    Abstract : One of the major hallmarks of cancer is aberrant or uncontrollable cell division, which occurs due to a defective cell cycle process. During the synthesis phase (S-phase) of the cell cycle, before cell division or mitosis phase, the DNA in the cell makes a new copy to pass on genetic information to the daughter cells. READ MORE