Search for dissertations about: "multiple myeloma"
Showing result 11 - 15 of 86 swedish dissertations containing the words multiple myeloma.
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11. Genetic analyses of multiple myeloma and related plasma cell dyscrasias
Abstract : Acquired genetic changes have proved to be of diagnostic and prognostic importance in different hematologic malignancies as well as in some solid tumor types. However, although multiple myeloma (MM), an incurable disease, and its proceeding stage monoclonal gammopathy of undetermined significance (MGUS) are quite common, little is known about the karyotypic features of these plasma cell dyscrasias. READ MORE
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12. Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy
Abstract : This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM is not fully understood and there is a large intra-tumour and interclonal genetic variation in MM patients. READ MORE
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13. Clinical studies in multiple myeloma
Abstract : Multiple Myeloma (MM) is an incurably disease of the bone marrow. It is characterized by the uncontrolled growth of clonal plasma cells (PCs) and leads to production of non-functional gammaglobulin. Clinical features include loss of normal bone marrow function, defect bone structure and kidney failure. READ MORE
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14. Neutrophils as Suppressor Cells and their role in Multiple Myeloma
Abstract : .... READ MORE
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15. Identification and characterization of DNA sequence variants associated with multiple myeloma
Abstract : Multiple myeloma (MM) is the second most common hematologic malignancy. The disease is characterized by an uncontrolled growth of malignant plasma cells in the bone marrow, producing a monoclonal immunoglobulin (“M protein”) that can be detected in peripheral blood. READ MORE