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Showing result 1 - 5 of 11 swedish dissertations matching the above criteria.

2. 1. Chronic sorrow and quality of life in patients with multiple sclerosis

   Author : Ann-Kristin Isaksson; Gerd Ahlström; Lars-Gunnar Gunnarsson; Siv Söderberg; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; illness experience; diagnosis experience; impairment; health-related quality of life; subjective quality of life; immunological treatment; chronic sorrow; depression; managing chronic illness; content analysis; well-being; Caring sciences; Vårdvetenskap; Vårdvetenskap; Nursing Science;

   Abstract : The overall aim of this thesis was to increase our understanding and knowledge of patients’ experiences of living with multiple sclerosis (MS). A mixed-method design was used, including both qualitative and quantitative methods. READ MORE

4. 2. Epidemiological and radiological aspects of multiple sclerosis

   Author : Anne-Marie Landtblom; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : The first aim of this investigation was to analyse possible risk factors for multiple sclerosis (MS) with focus on animal contacts and occupational exposures, especially to organic solvents. Another aim was to search for specific features in solvent-exposed MS patients mainly by the radiological techniques magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy ( 1 H MRS) and also by cerebrospinal fluid (CSF) analysis along with a disability scoring. READ MORE

5. 3. B-cell survival factors in multiple sclerosis and myasthenia gravis

   Author : Mathula Thangarajh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Multiple sclerosis (MS) is a chronic, progressive neurological disease in which death of myelin-producing oligodendrocytes and axonal damage are prominent pathological features. The cause of MS is unknown but genetic and environmental factors have been proposed to be important. READ MORE

6. 4. Amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations in British Columbia, Canada : clinical, neurophysiological and neuropathological features

   Author : Heather G. Stewart; Hiroshi Mitsumoto; Umeå universitet; []
   Keywords : ALS; SOD1; complete penetrance; incomplete penetrance; mis-diagnosis; upper motor neuron; clinical neurophysiology; transcranial magnetic stimulation; peristimulus time histogram; corticospinal pathway; cortical inhibition; cortical hyper-excitability;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neurons and their supporting cells in the brain, brainstem and spinal cord, resulting in muscle paresis and paralysis including the bulbar (speech, chewing, swallowing) and respiratory muscles. The average age at onset is 55 years, and death due to respiratory failure occurs 2-5 years after symptom onset in ~ 85% of cases. READ MORE

7. 5. Genetic Studies of Rheumatoid Arthritis using Animal Models

   Author : Niklas Nordquist; William Dietrich; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Complex disease; autoimmune; rheumatoid arthritis; genetic; mapping; QTL; locus; linkage; animal model; rat; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Abstract : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. READ MORE