Search for dissertations about: "multiple sclerosis HLA"

Showing result 1 - 5 of 43 swedish dissertations containing the words multiple sclerosis HLA.

2. 1. HLA genetics in multiple sclerosis

   Author : Jenny Link; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. READ MORE

4. 2. Immunogenetic studies of multiple sclerosis

   Author : Arturs Ligers; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Multiple sclerosis; CTLA-4; HLA-A2; HLA-A3; HLA-DRB1*15; HLA-DRB1*;

   Abstract : Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS). Several genetic factors are likely to be of importance for MS rather than one factor. READ MORE

5. 3. Genetic Analyses of Multiple Sclerosis and Systemic Lupus Erythematosus : From Single Markers to Genome-Wide Data

   Author : Johanna K Sandling; Ann-Christine Syvänen; Lovisa Lovmar; Joseph Terwilliger; Javier Martín Ibáñez; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; Multiple Sclerosis; Association study; Type I interferon system; Single nucleotide polymorphism; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

   Abstract : In autoimmune diseases an individual’s immune system becomes targeted at the body’s own healthy cells. The aim of this thesis was to identify genetic risk factors for the two autoimmune diseases multiple sclerosis (MS) and systemic lupus erythematosus (SLE). READ MORE

6. 4. Tobacco and multiple sclerosis susceptibility

   Author : Anna Karin Hedström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system (CNS) that arises from a combination of a complex genetic predisposition and environmental factors. For northern Europeans, the lifetime risk of MS is 1:400, making it the most common non-traumatic cause of disability in young adults. READ MORE

7. 5. Susceptibility gene mapping in multiple sclerosis

   Author : Bing He; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease characterized by relapsing or progressive demyelination of the central nervous system (CNS). Increasing evidence supports that genetic factors confer susceptibility to MS resulting in an unknown mode of inheritance as a complex trait. READ MORE