Search for dissertations about: "multiple sclerosis and respiratory dysfunction"

Found 2 swedish dissertations containing the words multiple sclerosis and respiratory dysfunction.

2. 1. Amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations in British Columbia, Canada : clinical, neurophysiological and neuropathological features

   Author : Heather G. Stewart; Hiroshi Mitsumoto; Umeå universitet; []
   Keywords : ALS; SOD1; complete penetrance; incomplete penetrance; mis-diagnosis; upper motor neuron; clinical neurophysiology; transcranial magnetic stimulation; peristimulus time histogram; corticospinal pathway; cortical inhibition; cortical hyper-excitability;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neurons and their supporting cells in the brain, brainstem and spinal cord, resulting in muscle paresis and paralysis including the bulbar (speech, chewing, swallowing) and respiratory muscles. The average age at onset is 55 years, and death due to respiratory failure occurs 2-5 years after symptom onset in ~ 85% of cases. READ MORE

4. 2. Biomedical factors in the risk and prognosis of amyotrophic lateral sclerosis

   Author : Jiangwei Sun; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a relatively rare but incurable and relentlessly progressive neurodegenerative disease, characterized by motor neuron loss in the brain and spinal cord. Majority of patients die within 3-5 years after symptom onset, commonly due to respiratory failure. READ MORE