Search for dissertations about: "multivariate analytical methods"

Showing result 11 - 15 of 51 swedish dissertations containing the words multivariate analytical methods.

2. 11. Adipose Tissue Heterogeneity - Development and Application of Nonlinear Microscopy Methods

   Author : Alexandra Paul; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; least squares decomposition; stem cells; multivariate spectral analysis; obesity; adipose tissue; adipogenesis; broadband coherent anti-Stokes Raman scattering; extracellular matrix;

   Abstract : Although the negative health impacts of obesity have been well documented, the number of overweight or obese patients has and is predicted to continue rising. One of the causal factors of obesity is a constant positive energy balance mainly from excessively high caloric intake from food compared with limited physical activity (caloric expenditure). READ MORE

4. 12. Metabolite Profiling of Drugs using Mass Spectrometry : Identification of analytical targets for doping control and improvements of the metabolite search process

   Author : Malin Nilsson Broberg; Mikael Hedeland; Ulf Bondesson; Curt Pettersson; Börje Tidstedt; Peter Van Eenoo; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; UHPLC-HRMS; Doping control; Metabolite profile; SARM; Selective Androgen Receptor Modulator; MVDA; Microsomes; Experimental design; Analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

   Abstract : Doping is defined as the use of prohibited substances or methods by the World Anti-Doping Agency and the aim with doping control analysis is to detect the use of these illicit substances or methods. Substances that are prohibited in human or equine sports have either a positive or negative impact on the performance. READ MORE

5. 13. Multidetection and chemometrics in flow injection analysis

   Author : Robert Tryzell; Elo H. Hansen; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Analytical Chemistry; analytisk kemi;

   Abstract : An ideal method for the determination of ions in aqueous solutions should be fast, inexpensive, simple, reliable and require small sample volumes. Flow Injection Analysis (FIA) is in many respects such an ideal method but it is too often limited to the determination of one analyte at a time. READ MORE

6. 14. Development of Protocols for Metabolomics in Biomedical Research using Chemometrics

   Author : Anders Danielsson; Centrum för analys och syntes; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; gas chromatography; design of experiments; Metabolomics; chemometrics; diabetes; metabolism; multivariate analysis;

   Abstract : Metabolomics is a rapidly growing research field. It aims for quantification of all the metabolites in a biological sample such as plasma, saliva, cerebrospinal fluid or cells. READ MORE

7. 15. Multi-platform metabolomics assays to study the responsiveness of the human plasma and lung lavage metabolome

   Author : Masoumeh Karimpour; Malin Nording L.; Magnus Åberg; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LC MS; GC MS; NMR; metabolomics; metabolite; exposure; postprandial; plasma; lung lavage; BW; BW; data analysis; univariate analysis; multivariate analysis;

   Abstract : Metabolomics as a field has been used to track changes and perturbations in the human body by investigating metabolite profiles indicating the change of metabolite levels over time and in response to different challenges. In this thesis work, the main focus was on applying multiplatform-metabolomics to study the human metabolome following exposure to perturbations, such as diet (in the form of a challenge meal) and exhaust emissions (air pollution exposure in a controlled setting). READ MORE