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Showing result 1 - 5 of 140 swedish dissertations matching the above criteria.
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1. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions
Abstract : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. READ MORE
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2. Multivariate Synergies in Pharmaceutical Roll Compaction : The quality influence of raw materials and process parameters by design of experiments
Abstract : Roll compaction is a continuous process commonly used in the pharmaceutical industry for dry granulation of moisture and heat sensitive powder blends. It is intended to increase bulk density and improve flowability. READ MORE
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3. Multivariate methods in tablet formulation
Abstract : This thesis describes the application of multivariate methods in a novel approach to the formulation of tablets for direct compression. It begins with a brief historical review, followed by a basic introduction to key aspects of tablet formulation and multivariate data analysis. READ MORE
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4. Aspects on probabilistic approach to design : From uncertainties in pre-investigation to final design
Abstract : Geotechnical engineering is strongly associated with large uncertainties. Exploring a medium (soil) that is almost entirely and completely hidden from us is no easy task. Investigations can be made only at discrete points, and the majority of a specific soil volume is never tested. READ MORE
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5. Essays on Sample Surveys : Design and Estimation
Abstract : Sampling is a core stage in every survey. A sampling design carefully elaborated may imply not only a more accurate estimation of the parameters of interest, but also a reduction in the required sample size in a study. In this thesis we consider two particular but connected subjects. READ MORE