Search for dissertations about: "multivariate evaluation"

Showing result 1 - 5 of 141 swedish dissertations containing the words multivariate evaluation.

  2. 1. Univariate and Multivariate Surveillance of Outbreaks

    Author : Linus Schiöler; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; change-points; expected delay; exponential family; false alarms; generalised likelihood; inference principles; influenza; MEWMA; monitoring; multivariate; ordered regression; performance metrics; outbreak; predictive value; subjective judgment; spatial; statistical models; surveillance; tularemia;

    Abstract : In many areas there is a need to monitor observations in order to detect changes in the underlying processes as quickly as possible. The theory of statistical surveillance provides the possibility of making optimal decisions about whether a change has occurred or not based on the data available at the time of the decision. READ MORE

  4. 2. Application of surface enhanced Raman spectroscopy and multivariate evaluation techniques on biological samples

    Author : Charlotte Eliasson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RS; PLS; multivariate evaluation; Raman spectroscopy; partial least squares; PCA; principal component analysis; SERS; surface-enhanced Raman Spectroscopy; chemometrics; doxorubicin;

    Abstract : .... READ MORE

  5. 3. Multivariate profiling of metabolites in human disease : Method evaluation and application to prostate cancer

    Author : Elin Thysell; Henrik Antti; Janne Lehtiö; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolite profiling; metabolomics; predictive metabolomics; mass spectrometry; GC-MS; biomarkers; chemometrics; design of experiments; multivariate data analysis; prostate cancer; bone metastases; plasma; biologisk kemi; biological chemistry;

    Abstract : There is an ever increasing need of new technologies for identification of molecular markers for early diagnosis of fatal diseases to allow efficient treatment. In addition, there is great value in finding patterns of metabolites, proteins or genes altered in relation to specific disease conditions to gain a deeper understanding of the underlying mechanisms of disease development. READ MORE

  6. 4. Exploration of Multivariate Evaluation Techniques in Surface Enhanced Raman Spectroscopy (SERS)

    Author : Aamer Abbas; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carotenoids; surface enhanced raman spectroscopy; orthogonal partial least squares; target orthogonal partial least squares; chemical imaging; OPLS; PLS; cytarbine; raman; hyperspectral; idarubicin; T-OPLS; doxorubicin; lymphocytes; multivariate analysis; 4-mercaptobenzonitrile; internal standard;

    Abstract : .... READ MORE

  7. 5. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions

    Author : David Andersson; Anna Linusson Jonsson; Gabriele Cruciani; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular docking; chemometrics; multivariate analysis; principal component analysis; PCA; design of experiments; DoE; partial least-square projections to latent structures; PLS; scoring functions; ligand-binding cavity; major histocompatibility complex; MHC; glycopeptide; T-cell.; Pharmaceutical chemistry; Läkemedelskemi; datorlingvistik; computational linguistics;

    Abstract : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. READ MORE