Search for dissertations about: "murine pneumotropic virus"

Found 4 swedish dissertations containing the words murine pneumotropic virus.

  2. 1. Studies on the Molecular Biology of the Mouse Pneumotropic Polyomavirus

    Author : Shouting Zhang; Kristina Dörries; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; murine pneumotropic virus; Kilham mouse polyomavirus; large T antigen; enhancer; regulatory region rearrangement; gene expression regulation; DNA replication; transposable elements; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The Murine Pneumotropic Virus (MPtV), in contrast to the other MurinePolyomavirus (MPyV), appears to be non-tumourigenic in its natural host. Instead, MPtV causes acute pneumonia and can serve as a model in studies of polyomavirus-induced disease. In initial experiments, MPtV large T-antigen (LT) was expressed in a heterologous system. READ MORE

  4. 2. Vaccination against Her2/neu : expressing cancer using chimeric virus-like particles

    Author : Kalle Andreasson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Thanks to the development of vaccines, children are these days protected against infectious diseases like polio, diphtheria and tetanus simply by receiving a few injections. Imagine a scenario where these injections would also result in protection against cancer. READ MORE

  5. 3. Studies on polyomavirus virus-like particles : as vaccines and vectors for immune and gene therapy

    Author : Karin Tegerstedt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Polyomavirus; virus-like particles; immunotherapy; Her2 and dendritic cells;

    Abstract : Virus-like particles (VLPs) are similar to natural virus particles except that they lack viral genes. They have a similar cellular uptake to the natural virus from which they are derived but are non-infectious and can therefore not reproduce themselves. READ MORE

  6. 4. Cancer therapy using viral and bacterial proteins as vectors for vaccines or as carriers of cytostatics

    Author : Mathilda Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : New cancer therapies are urgently needed, since available treatment options today have negative side effects, and cure only about half of the patients with invasive cancer. One, relatively new, option is to vaccinate against cancer, by introducing an antigen that is present on the tumor cells into the patient to stimulate specific immunity against the tumor. READ MORE