Search for dissertations about: "muscarinic receptor"
Showing result 1 - 5 of 64 swedish dissertations containing the words muscarinic receptor.
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1. Muscarinic receptors and urinary bladder selectivity : Properties that determine the organ selectivity of compounds
Abstract : Urinary bladder contraction is mainly mediated by activation of muscarinic acetylcholine receptors (mAChR). Muscarinic antagonists are often effective in treatment of unstable bladder. The effectiveness of this treatment has often been limited by side effects as dry mouth. READ MORE
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2. Muscarinic Receptors in the Urinary Bladder - The role of the urothelium regarding cholinergic and nitrergic effects in inflammation
Abstract : Inflammation alters the functional properties of the urinary bladder. Interstitial cystitis (IC) is a chronic inflammatory syndrome in man that is characterized by urgency, frequency and visceral pain. READ MORE
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3. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement
Abstract : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. READ MORE
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4. Muscarinic acetylcholine receptors : investigation of interactions with agonists and antagonists
Abstract : In the present investigation interactions of agonists and antagonists with the muscarinic acetylcholine receptor from rat cerebral cortex and rat ileum smooth muscle have been characterized.It is suggested that the binding of antagonist involves two sequential equilibria, an association reaction followed by isomerization of the receptor-antagonist complex. READ MORE
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5. Investigation on Pre- and Postsynaptic Ca2+ Signaling in Neuronal Model Systems
Abstract : Communication between neuronal and non-neuronal is called volume transmission when the released neurotransmitter (NT) acts via diffusion and affects several target cells. Both the neurosecretory and postsynaptic cell responses are linked to [Ca2+]i elevations. READ MORE