Search for dissertations about: "muscle forces"
Showing result 16 - 20 of 61 swedish dissertations containing the words muscle forces.
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16. Characterization and applications in muscle of a Minicircle vector for Nonviral gene therapy
Abstract : In gene therapy, the aim is to change the behaviour of a cell by introduction of genetic material, often DNA encoding a protein or a therapeutic RNA. The purpose can be to replace a malfunctioning copy of a gene, as in clinical trials for treatment of X-linked severe combined immunodeficiency, or introduce a new gene into the body to help fight a disease, as has been done in clinical trials for e. READ MORE
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17. Vascular smooth muscle mechanotransduction and plasticity-the role of microRNA, calcium signaling and actin polymerization
Abstract : Smooth muscle cells residing in the blood vessel media are constantly exposed to mechanical forces exerted by the intraluminal pressure. The smooth muscle senses and adapts to mechanical forces by activation of multiple signaling pathways and cytoskeletal rearrangements. READ MORE
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18. Towards a human body model for prediction of vehicle occupant kinematics in omni-directional pre-crash events
Abstract : As the vehicle fleet becomes more equipped with crash avoidance systems, the proportion of crashes preceded by evasive manoeuvres is expected to increase. In an evasive manoeuvre, occupant position and posture can be influenced by the induced loading. Therefore, there is a need to predict the occupant response from evasive manoeuvres. READ MORE
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19. Middle ear mechanics : using temporal bone experiments to improve clinical methods
Abstract : BackgroundThe middle ear transmits and amplifies sound vibrations from the tympanic membrane via three ossicles to the inner ear. Moreover, it contains two muscles, the stapedius muscle (SM) which protects the inner ear from loud noise, and the tensor tympani (TT) whose function is still debated. READ MORE
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20. Effects of Biomechanical Stress on Gene Regulation in Vascular Cells
Abstract : The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. READ MORE