Search for dissertations about: "muscle system"

Showing result 11 - 15 of 537 swedish dissertations containing the words muscle system.

  1. 11. Genetic studies of zebrafish muscles : clues to protection in muscle disease

    Author : Nils Dennhag; Fatima Pedrosa Domellöf; Jonas von Hofsten; Tatjana Haitina; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; zebrafish; muscle; extraocular muscles; intermediate filaments; bioinformatics; genetics; CRISPR Cas9; oftalmiatrik; ophthalmology; cellforskning; cell research;

    Abstract : Muscular dystrophies (MDs) are caused by dysregulation of over 40 proteins but commonly share features of muscle weakness, myofiber death and regeneration, loss of ambulation and premature death. A MD involves a broken link anywhere in the connection from extracellular matrix through the sarcolemma to the sarcomere. READ MORE

  2. 12. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies

    Author : Lena Carlsson; Lars-Eric Thornell; Anders Arnér; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; desmin; nestin; synemin; paranemin; plectin; αB-crystallin; skeletal muscle; heart muscle; myotendinous junction; motor endplate; costamere; anatomi; Human Anatomy;

    Abstract : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. READ MORE

  3. 13. MUSCLE TONE IMBALANCE IN HUMAN UPPER EXTREMITY An experimental study of muscle adaptation to altered tension

    Author : Fredrik Einarsson; Göteborgs universitet; []
    Keywords : muscle biopsy; freeze storage; upper extremity; shoulder; human muscle; sarcomere; stress-strain relationship; stress relaxation; stiffness; elasticity; mechanical testing; morphology; spasticity; obstetric brachial plexus palsy; rotator cuff tear; tendon transfer;

    Abstract : Aim: The aim of this thesis was to improve outcome after tendon transfer and rotator cuff surgery by investigating the impact on response to passive mechanical testing and change in structural characteristics associated with longstanding changes in the tension of skeletal muscle in the human upper extremities in vivo. Patients and methods: The investigational method was in vitro assessment of human upper extremity muscles. READ MORE

  4. 14. Experimental studies of spinal mechanisms associated with muscle fatigue

    Author : Ivana Kalezic; Vito Enrico Pettorossi; Umeå universitet; []
    Keywords : muscle fatigue; monosynaptic reflex; presynaptic inhibition; recurrent inhibition; fusimotor system; Fos-immunoreactivity; referral pain; kirurgi; Surgery;

    Abstract : Muscle fatigue is ubiquitous in every day life.Muscle fatigue might be considered as an altered state of motor behaviour, which impairs motor performance. By contrast, muscle fatigue could also be considered a positive phenomenon, which protects muscle tissue from damage that might be incurred to it by overuse. READ MORE

  5. 15. Brain processing of experimental muscle pain and its interrelation with proprioception and muscle fatigue : positron emission tomography study

    Author : Alexander Korotkov; Docent Tomas Graven-Nielsen; Umeå universitet; []
    Keywords : Experimental muscle pain; Hypertonic saline; Kinesthesia; Proprioception; Movement; Vibration; Muscle fatigue; Brain; Imaging; Positron emission tomography; Regional cerebral blood flow;

    Abstract : Chronic muscle pain is a significant medical and social problem and better understanding of the pathophysiological mechanisms involved is an important requirement for further development of diagnostics, treatment and rehabilitation methods. Experimental imaging studies have investigated functional neuroanatomy of different pain components. READ MORE