Search for dissertations about: "mutation models"

Showing result 1 - 5 of 178 swedish dissertations containing the words mutation models.

  2. 1. Short and long-term effects of exposure to low dose and low dose rate of gamma radiation : using in vitro and in vivo models

    Author : Traimate Sangsuwan; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Low dose; Low dose rate; High dose rate; Ionizing radiation; Adaptive response; Senescence; Premature senescence; Oxidative stress; Drosophila embryo; Mutation; DNA repair; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Assessment of human health risks from exposure to ionizing radiation (IR) is mainly based on the extrapolation of results from epidemiological studies on populations exposed to relatively high doses and often at high dose rates (HDR). Risk estimates after exposure to low doses and in particular at low dose rates (LDR) remain controversial due to a lack of epidemiological evidence. READ MORE

  4. 2. Mathematical Models of Molecular Evolution

    Author : Martin Nilsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dynamic fitness landscapes; quasispecies; error thresholds; evolved mutation rates; evolution in dynamic environments;

    Abstract : This thesis deals with mathematical models of Darwinian evolution in populations of simple living organisms. We study models which describe how the representation of different gene sequences in the population is affected by the fundamental forces of evolutionary processes, such as selection pressure, the mutation rate and the time dynamics of the underlying fitness landscape. READ MORE

  5. 3. Investigation of radiation-induced genetic and epigeneticeffects using cultured cells and Drosophila as experimental models: with focus on dose rate

    Author : Traimate Sangsuwan; Siamak Haghdoost; Ulrich Theopold; Stenerlöw Bo; David Berger; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gamma radiation; low-dose-rate; MTH1; MYH; mutant frequency; Drosophila milanogaster; embryogenesis; mutation; molekylär biovetenskap; Molecular Bioscience;

    Abstract : .... READ MORE

  6. 4. Bayesian networks: exact inference and applications in forensic statistics

    Author : Ivar Simonsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bayesian networks; variable elimination algorithm; forensic statistics; relationship inference; mutation models; relationship inference;

    Abstract : Exact inference on Bayesian networks has been developed through sophisticated algorithms. One of which, the variable elimination algorithm, identifies smaller components of the network, called factors, on which local operations are performed. In principle this algorithm can be used on any Bayesian network. READ MORE

  7. 5. Exact inference in Bayesian networks and applications in forensic statistics

    Author : Ivar Simonsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; forensic statistics; familial relationship inference; Bayesian networks; variable elimination; exact inference; mutation models;

    Abstract : Bayesian networks (BNs) are commonly used when describing and analyzing relationships between interacting variables. Approximate methods for performing calculations on BNs are widely used and well developed. READ MORE