Search for dissertations about: "mutation rate"

Showing result 1 - 5 of 146 swedish dissertations containing the words mutation rate.

  1. 1. Mutations and Mutation Rate in the Development of Fluoroquinolone Resistance

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Patricia Komp Lindgren; Uppsala universitet.; [2007]
    Keywords : Microbiology; Mutation rate; Fluoroquinolone; Resistance; Biological fitness; Urinary tract infection; Escherichia coli; MPC; Mikrobiologi;

    Abstract : The emergence of multidrug resistant bacteria world wide is a serious problem, and very few new drugs are under development. The selection of resistant bacteria is affected by factors such as mutation rate, biological fitness cost and the rate of fitness compensation. READ MORE

  2. 2. Mutation and Diversity in Avian Sex Chromosomes

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hannah Sundström; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; mutation rate; diversity; sex chromosomes; indels; male bias; selective sweep; effective population size; birds; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik;

    Abstract : Sex chromosomes are useful for the study of how factors such as mutation, selection, recombination and effective population size affect diversity and divergence.A comparison of gametologous introns in seven different bird species revealed a complete lack of diversity on the female-specific W chromosome. READ MORE

  3. 3. Investigation of radiation-induced genetic and epigeneticeffects using cultured cells and Drosophila as experimental models: with focus on dose rate

    University dissertation from Stockholm University

    Author : Traimate Sangsuwan; Stockholms universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gamma radiation; low-dose-rate; MTH1; MYH; mutant frequency; Drosophila milanogaster; embryogenesis; mutation; molekylär biovetenskap; Molecular Bioscience;

    Abstract : .... READ MORE

  4. 4. Long QT syndrome in Sweden founder effects and associated cardiac phenotypes

    University dissertation from Umeå : Umeå universitet

    Author : Annika Winbo; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long QT Syndrome; Jervell and Lange-Nielsen Syndrome; inherited arrhythmia; founder effects; clinical genetics; haplotype analysis; mutation age; founder mutation; clinical phenotype; life-threatening cardiac events; mutation-specific; KCNQ1 gene; modifier genes; sequence variants; risk stratification; risk factor; gender; Pediatrics; pediatrik;

    Abstract : Background: We aimed to increase the knowledge regarding the familial arrhythmogenic disorder Long QT Syndrome (LQTS) and its recessive variant Jervell and Lange-Nielsen Syndrome (JLNS) in Sweden, including prevalences and clinical phenotypes. A specific focus was directed towards two KCNQ1 mutations –p.Y111C and p. READ MORE

  5. 5. Comparative Genomics in Birds

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Axelsson; Uppsala universitet.; [2007]
    Keywords : Molecular genetics; Birds; molecular evolution; macrochromosomes; microchromosomes; mutation rate; substitution rate; base composition; positive selection; genetic drift; population size; Genetik;

    Abstract : To shed light on forces that shape the molecular evolution of bird genomes, and in turn avian adaptations, comparative analyses of avian DNA sequences are important. Moreover, contrasting findings in birds to those of other organisms will lend a clearer view on general aspects of molecular evolution. READ MORE