Search for dissertations about: "myasthenia gravis"

Showing result 11 - 15 of 30 swedish dissertations containing the words myasthenia gravis.

  2. 11. CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis

    Author : XiongBiao Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cytotoxic-T-lymphocyte-associated antigen 4 CTLA-4 ; Myasthenia gravis MG ; Immune inhibitory receptor; Autoimmune disease; Genetic polymorphism.;

    Abstract : Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) plays a global inhibitory role in the immune system and has a crucial role in autoimmunity. READ MORE

  4. 12. Genetic factors predisposing to myasthenia gravis and related autoimmune disorders

    Author : Ryan Ramanujam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Myasthenia gravis (MG) is an autoimmune disorder in which patients experience weakness of the skeletal or ocular-bulbar muscles. In most patients, anti-AChR antibodies affect the signal across the neuromuscular junction necessary for muscular contraction. READ MORE

  5. 13. B-cell survival factors in multiple sclerosis and myasthenia gravis

    Author : Mathula Thangarajh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic, progressive neurological disease in which death of myelin-producing oligodendrocytes and axonal damage are prominent pathological features. The cause of MS is unknown but genetic and environmental factors have been proposed to be important. READ MORE

  6. 14. T lymphocytes and cytokines in the pathogenesis of experimental autoimmune myasthenia gravis

    Author : Guang-Xian Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Experimental autoimmune myasthenia gravis (EAMG), induced in different animal species and strains by immunization with nicotinic acetylcholine receptor (AChR) and complete Freund's adjuvant (CFA), represents an experimental model of myasthenia gravis (MG) in humans. Both MG and EAMG are autoimmune diseases mediated by antibodies against AChR of neuromuscular junctions. READ MORE

  7. 15. The electrophysiological topography of the motor unit in muscular dystrophy and in myasthenia gravis

    Author : Per Hilton-Brown; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE