Search for dissertations about: "myelin"

Showing result 16 - 20 of 127 swedish dissertations containing the word myelin.

  2. 16. Studies on T cells and cytokines in Guillain-Barré syndrome and experimental allergic neuritis

    Author : Charlotte Rüdhmer-Dahle; Jan Ernerudh; Jan Hillert; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Guillain-Barrésyndrome (GBS) is an inflammatory disease of peripheral nerves, characterised by muscle weakness. The nerves are attacked and destroyed by the immune system. The symptoms usually progress over a few weeks and many patients become severely disabled. READ MORE

  4. 17. Deciphering and fine-tuning of myeloid cells in CNS demyelinating conditions

    Author : Keying Zhu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Demyelination in the central nervous system (CNS) is a characteristic of various neurological disorders, such as multiple sclerosis (MS), neuromyelitis optica (NMO), subacute combined degeneration (SCD), tabes dorsalis (syphilitic myelopathy), and more. Although the causes vary, CNS demyelination is often associated with a significant buildup of inflammatory activated myeloid cells, mainly consisting of CNS resident microglia and infiltrating monocyte-derived macrophages. READ MORE

  5. 18. Polyneuropathy associated with monoclonal gammopathy : A clinical, neurophysiological and immunological study

    Author : Magnus Vrethem; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : This thesis is based upon clinical, neurophysiological, and immunological studies of polyneuropathy (symmetrical impairment of sensory and motor nerve function) in patients with monoclonal gammopathies, that is, patients characterized by proliferation of a plasma-cell clone secreting homogeneous immWloglobulins (M-component), which in some patients has serum antibody reactivity against peripheral nerve myelin.The prevalence of clinical polyneuropathy in patients with monoclonal gammopathy (n=3) was 36%, and the prevalence of all forms of polyneuropathy including patients with neurophysiological signs only andpatients with probable polyneuropathy (signs but no symptoms) was 58%. READ MORE

  6. 19. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies

    Author : Johanna Flygt; Niklas Marklund; Fredrik Piehl; Uppsala universitet; []
    Keywords : Traumatic brain injury; oligodendrocytes; oligodendrocyte progenitor cells; interleukin 1-β; central fluid percussion injury; Neurokirurgi; Neurosurgery; Neurokirurgi; Neurosurgery;

    Abstract : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. READ MORE

  7. 20. Temporal dynamics of brain plasticity : characterizing brain structural changes during skill acquisition

    Author : Tomás Mediavilla; Daniel Marcellino; Alexandra Badea; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Motor learning; brain plasticity; structural plasticity; magnetic resonance imaging; voxel-based morphometry; tractography; connectivity; motor cortex; posterior parietal cortex; cerebellum; vesicular glutamate transporter;

    Abstract : Traditionally, structural plasticity in the human brain has been considered to follow a linear or asymptotic increase over the course of training. However, recent studies using structural MRI revealed transient increases in grey matter volume (GMV) with learning. READ MORE