Search for dissertations about: "myeloid leukemia"

Showing result 6 - 10 of 195 swedish dissertations containing the words myeloid leukemia.

  2. 6. Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry

    Author : Lovisa Vennström; Göteborgs universitet; []
    Keywords : Acute leukemia; population-based; incidence; survival; acute myeloid leukemia; acute lymphoblastic leukemia; acute promyelocytic leukemia; early death;

    Abstract : Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features. READ MORE

  4. 7. Cell Surface Markers as Therapeutic Targets in Myeloid Leukemia

    Author : Niklas Landberg; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CML; AML; Cell surface markers; Leukemic stem cells; Myeloid leukemia; Antibody-based targeting; CML; AML; Cell surface markers; Leukemic stem cells; Myeloid leukemia; Antibody-based targeting;

    Abstract : .... READ MORE

  5. 8. Optimizing Chemotherapy in Childhood Acute Myeloid Leukemia

    Author : Josefine Palle; Gudmar Lönnerholm; Britt-Marie Frost; Rolf Larsson; Henrik Schröder; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood; acute myeloid leukemia; drug resistance; pharmacokinetics; chromosomal abnormalities; Down syndrome; MLL-rearrangement; t 9; 11 ; Paediatric medicine; Pediatrisk medicin;

    Abstract : Despite major advances in our understanding of the biology of childhood acute myeloid leukemia (AML) and the development of new cytotoxic drugs, the prognosis of long-term survival is still only 60-65 %.In the present research, we studied the pharmacokinetics of drugs used in the induction therapy of childhood AML and performed in vitro drug sensitivity testing of leukemic cells from children with AML. READ MORE

  6. 9. Targeting Nutrient Transporters in Acute Myeloid Leukemia

    Author : Hannah Åbacka; Medicinsk strukturbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Akut myeloisk leukemi; Metabolism; Transportörer; GLUT1; GLUT4; CD36; AQP7; ASPL; Inhibitor; Glukos; Fettsyra; Glycerol; Acute myeloid leukemia; Metabolism; Transporter; GLUT1; GLUT4; CD36; AQP7; ASPL; Small-molecule inhibitor; Glucose; Fatty acid; Glycerol;

    Abstract : .... READ MORE

  7. 10. Clinical and Experimental Studies in Chronic Myeloid Leukemia : Studies of Treatment Outcome, In Vitro Cellular Drug Resistance and Gene Expression

    Author : Ulla Olsson-Strömberg; Bengt Simonsson; Elin Lindhagen; Gisela Barbany; Johan Richter; Uppsala universitet; []
    Keywords : Medicine; chronic myeloid leukemia; adult; stem cell transplantation; mobilization of Ph-negative stem cells; in vitro assay; imatinib; gene expression; Medicin;

    Abstract : The aims of the studies described in the thesis were to investigate different treatment strategies in chronic myeloid leukemia (CML) patients. Furthermore, activity of imatinib was investigated by in vitro cytotoxicity assay, and the gene expression pattern in interferon treated patients. READ MORE