Search for dissertations about: "myocardial fibrosis"

Showing result 1 - 5 of 20 swedish dissertations containing the words myocardial fibrosis.

  2. 1. Assessment of myocardial viability using magnetic resonance imaging

    Author : Robert Jablonowski; Lund Klinisk fysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; myocardial infarction; hypertrophic cardiomyopathy; fibrosis; viability;

    Abstract : Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. READ MORE

  4. 2. Insights into left atrial response to pressure and volume overload

    Author : Matteo Lisi; Michael Henein; Sergio Mondillo; Lars-Åke Lars; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keywords Mitral regurgitation; aortic stenosis; speckle tracking echocardiography; heart transplantation; left atrial strain; left ventricualr function; right ventricular function; myocardial fibrosis;

    Abstract : The general purpose of this thesis is to establish the ability of Speckle Tracking Echocardiography (STE) in assessing left atrial (LA) response to pressure and volume overload respectively in aortic stenosis (AS) and mitral regurgitation (MR), and to evaluate its accuracy in predicting LA and right ventricular (RV) fibrosis in patients with end-stage heart failure (HF) undergoing heart transplantation (HTx).I demonstrated that assessment of left ventricular (LV) long axis systolic velocity and amplitude of excursion is more sensitive than simple determination of ejection fraction (EF) for revealing the beneficial impact of MR surgery on overall LV systolic performance. READ MORE

  5. 3. Role of extracellular retention of platelet-derived growth factor-B. Functions in development and disease

    Author : Per Lindblom; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; pericyte; cancer; fibrosis; ECM; HSPG; cell retention; endothelial;

    Abstract : During development, the cell secretes growth and differentiation factors (GDFs) to the surrounding microenvironment. These factors are often key regulators of organogenesis and embryogenesis. Several GDFs carry sequences that mediate specific interaction with molecules of the extracellular matrix (ECM) that surrounds the cell. READ MORE

  6. 4. Myocardial Tissue Characterization Using Magnetic Resonance Imaging

    Author : Sofia Kvernby; Tino Ebbers; Jan Bertus Marcel Warntjes; Jan Engvall; Agnetha Gustafsson; Per Thunberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In cardiovascular disease, which is the most common cause of death in the world, early diagnosis is crucial for disease outcome. Diagnosis of cardiovascular disease can be challenging, though. READ MORE

  7. 5. PET in Heart Failure - Methods and Applications

    Author : Jens Sörensen; Göran Hedenstierna; Elisabeth Ståhle; Bengt Långström; Juhani Knuuti; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; congestive heart failure; myocardial ischemia; positron emission tomography; left ventricular dysfunction; tracer kinetic models; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : Positron Emission Tomography (PET) permits regional myocardial perfusion, fibrosis and oxidative metabolism to be non-invasively quantified with radioactive tracers such as [15O]-water and [1-11C]-acetate. PET is an established research tool in congestive heart failure (CHF), a major cause of morbidity and mortality. READ MORE