Search for dissertations about: "myocardin"

Showing result 1 - 5 of 6 swedish dissertations containing the word myocardin.

  2. 1. Regulation of gene expression in the vascular wall

    Author : Erik Larsson; Göteborgs universitet; []
    Keywords : smooth muscle; endothelium; angiogenesis; SRF; myocardin; LPP; gene regulation; genetics; microRNA;

    Abstract : Blood vessel growth and function are closely related to a number of pathological conditions, including tumor angiogenesis, wound healing and atherosclerosis. Smooth muscle cells (SMC) and endothelial cells (EC), the two major constituents of the vascular wall, are both characterized by the expression of unique phenotypic marker genes, many of which have vital roles in blood vessel development and disease. READ MORE

  4. 2. New insight into myocardin regulation and function in smooth muscle cells

    Author : Li Liu; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Contractility; Inflammation; Muscarinic receptor; Myocardin-related transcription factors; Phenotypic modulation; Smooth muscle; SRF; WWTR1; YAP1;

    Abstract : Smooth muscle cells (SMCs) are constituents of hollow inner organs. Their contractile function governs essential physiological functions, such as breathing, eating, blood pressure control, urination, and childbirth. READ MORE

  5. 3. Transcriptional control mechanisms in the wall of the urinary bladder. Myocardin family coactivators and the transcriptomic impact of denervation

    Author : Baoyi Zhu; Cellulär biomekanik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Urological problems can be caused by diseases that affect the bladder wall and its innervation. Contraction and relaxation of smooth muscle cells (SMCs) is essential for maintaining detrusor function and for emptying the bladder. READ MORE

  6. 4. Developmental origin and molecular regulation of vascular smooth muscle cells

    Author : Per Wasteson; Göteborgs universitet; []
    Keywords : smooth muscle cell; aorta; cell origin; lateral plate mesoderm; paraxial mesoderm; lipoma preferred partner; serum response factor; neointimal hyperplasia; angiotensin II; platelet-derived growth factor-B;

    Abstract : Several pathologies of the vascular system have been suggested to be dependent on the smooth muscle cells (SMCs) that build up the vessel wall. Aortic SMCs have been proposed to derive from lateral plate mesoderm. READ MORE

  7. 5. Transcriptional control in the vascular wall. Actin-responsive coactivators and smooth muscle transcripts

    Author : Katarzyna Krawczyk; Cellulär biomekanik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cardiovascular disease (CVD) is the leading cause of death globally. In the European Union (EU) alone, CVD accounts for 1.8 million deaths each year. CVD is a group of disorders involving the heart and the blood vessels. READ MORE