Search for dissertations about: "myosin"

Showing result 1 - 5 of 103 swedish dissertations containing the word myosin.

  1. 1. Myosin myopathy. A new disease entity

    Author : Homa Tajsharghi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Neuromuscular disorders; Myosin myopathy; Myosin heavy chain; Myosin storage myopathy;

    Abstract : By the discovery and characterization of two familial myopathies caused by mutations in myosin heavy chaingenes, we introduce a new entity within the field of neuromuscular disorders: Myosin myopathyThe first myopathy affected a family in western Sweden. Previous linkage analysis had located the gene tochromosome 17p13. READ MORE

  2. 2. Towards Myosin Powered Lab-on-a-Chip Devices

    Author : Lasse ten Siethoff; Alf Månsson; Miklos Kellermayer; Linnéuniversitetet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; myosin; actin; molecular motors; lab-on-a-chip; nanobiotechnology; bionanotechnology; diagnostics; nanowires; nanowire arrays; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Myosins are protein motors that use chemical energy in the form of adenosinetriphosphate to produce force and motion. These molecular motors might be usedto power transportation in Lab-on-a-chip devices where a series of laboratory tasks(e.g. separation, concentration and detection) are performed in one sequence on asmall chip. READ MORE

  3. 3. Actomyosin in biocomputation

    Author : Aseem Salhotra; Alf Månsson; Henry Hess; Linnéuniversitetet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; biocomputation; molecular motors; 3-SAT; surface chemistry; actomyosin; actin; myosin II; heavy meromyosin; myosin XI; engineered myosin; in vitro motility assay; nanofabrication; alternate computing; network based biocomputation; protein-surface interaction; longevity; prolongation; surface recycling; affinity purification; blocking actin; Bioteknik; Biotechnology; Biokemi; Biochemistry;

    Abstract : There exist complex mathematical problems that are important in real world applications such as weather prediction, molecular modelling, network route optimization and more. In general, such problems are solved using supercomputers with higher computing efficiency but this also consumes high energy along with high production and maintenance cost. READ MORE

  4. 4. Variability and adaptation in the contractile system of smooth muscle

    Author : Mia Löfgren; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; essential light chain; desmin; shortening velocity; integrin; intermediate filament; hypertrophy; non-muscle myosin; smooth muscle; myosin; heavy chain; Physiology; Fysiologi;

    Abstract : This thesis examines the cellular and molecular mechanisms involved in the large diversity of the contractile properties in smooth muscle. Six studies, I-VI, are included. I: a slow smooth muscle (aorta) has a different nucleotide and phosphate dependence compared to a fast type (taenia coli). READ MORE

  5. 5. Study the role of patient-specific mutations by genetic disease modeling : From gene to function; A study to understand muscles

    Author : Martin Dahl-Halvarsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Muscles; Myosin; MYH7; Myosin storage myopathy; Laing early-onset myopathy; Drosophila; TOR1A; DYT1; HCM; heart disease;

    Abstract : Many genetic diseases inherited in a dominant fashion have a complex pathological pattern. TOR1A mediated Dystonia-1 (DYT1) is an example of incomplete penetrance, affecting only a third of the carriers. READ MORE