Search for dissertations about: "n-acetyl-cysteine"
Found 4 swedish dissertations containing the word n-acetyl-cysteine.
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1. Diagnostic and therapeutic strategies following spinal cord and brachial plexus injuries
Abstract : Traumatic injuries to the spinal cord and brachial plexus induce a significant inflammatory response in the nervous tissue with progressive degeneration of neurons and glial cells, and cause considerable physical and mental suffering in affected patients. This thesis investigates the effects of the antioxidants N-acetyl-cysteine (NAC) and acetyl-L- carnitine (ALC) on the survival of motoneurons in the brainstem and spinal cord, the expression of pro-apoptotic and pro-inflammatory cell markers, axonal sprouting and glial cell reactions after spinal hemisection in adult rats. READ MORE
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2. Sensory neuronal protection & improving regeneration after peripheral nerve injury
Abstract : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. READ MORE
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3. Skeletal muscle plasticity and energy metabolism
Abstract : Skeletal muscle is remarkable in its ability to adjust to our needs. It can change its energy stores and usage, as well as its total mass. Furthermore, skeletal muscle adapts to deactivate reactive oxygen species produced, which in turn can both damage cells and convey signals. READ MORE
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4. Neuroprotection and axonal regeneration after peripheral nerve injury
Abstract : Following microsurgical reconstruction of injured peripheral nerves, severed axons are able to undergo spontaneous regeneration. However, the functional result is always unsatisfactory with poor sensory recovery and reduced motor function. READ MORE