Search for dissertations about: "n6"

Showing result 1 - 5 of 13 swedish dissertations containing the word n6.

  2. 1. DNA adducts as biomarkers of exposure to some dietary carcinogens

    Author : Tina Jurén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Humans are exposed to many chemicals via intake of food and drink and there are strong associations between dietary factors and cancer. Exposure to the dietary carcinogens acrylamide and acetaldehyde are potential health risks that have made the headlines. High levels of acrylamide are found in various food items, such as potato chips. READ MORE

  4. 2. Ribosomal RNA Modification Enzymes : Structural and functional studies of two methyltransferases for 23S rRNA modification in Escherichia coli

    Author : Avinash S. Punekar; Maria Selmer; Martino Bolognesi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; ribosome biogenesis; ribosome assembly; ribosomal RNA; peptidyltransferase center; domain V; post-transcriptional modification; methyltransferases; S-adenosyl-methionine; RlmM; Cm2498; RlmJ; m6A2030; X-ray crystallography; substrate recognition; substrate specificity; catalytic mechanism; evolution; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry;

    Abstract : Escherichia coli ribosomal RNA (rRNA) is post-transcriptionally modified by site-specific enzymes. The role of most modifications is not known and little is known about how these enzymes recognize their target substrates. READ MORE

  5. 3. Accuracy of protein synthesis and its tuning by mRNA modifications

    Author : Gabriele Indrisiunaite; Måns Ehrenberg; Suparna Sanyal; Jaanus Remme; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Protein synthesis; Translation; Accuracy; Release factor; Termination; mRNA modifications; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The ribosome is a large macromolecular complex that synthesizes all proteins in the cell in all kingdoms of life. Proteins perform many vital functions, ranging from catalysis of biochemical reactions to muscle movement. It is essential for cells and organisms that proteins are synthesized rapidly and accurately. READ MORE

  6. 4. Excitation and Ground-State Properties of Natural and Modified Nucleic Acid Bases

    Author : Anders Holmén; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ab initio; linear dichroism; DFT; transition moment; tautomerism; structure; IR; spectra; DNA bases;

    Abstract : The nucleic acid bases are the carriers of genetic information in DNA and RNA. They are also the main chromophores of nucleic acids and determine their optical properties and sensitivity to UV radiation. READ MORE

  7. 5. Adenosine action on platelets : pharmacological and functional studies in human platelets in vitro

    Author : Ulla Söderbäck; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adenosine; adenosine analogs; methylxanthines; cyclic AMP; ADP; dipyridamole; platelet-rich plasma; whole blood aggregatron; human. Ulla SöderbäckAdenosine action on platelets. Pharmacological and functional studies in human pl;

    Abstract : The endogenous purine adenosine (ADO) is known to inhibit platelet aggregation in vitro through increased platelet levels of cyclic AMP. This effect is ADO-A2-receptor-mediated through stimulation of membrane adenylyl cyclase. READ MORE