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Showing result 1 - 5 of 24 swedish dissertations matching the above criteria.

  1. 1. Novel Interventions in Cardiac Arrest : Targeted Temperature Management, Methylene Blue, S-PBN, Amiodarone, Milrinone and Esmolol,  Endothelin and Nitric Oxide In Porcine Resuscitation Models

    Author : Frank Zoerner; Fredrik Lennmyr; Cécile Martijn; Lars Wiklund; Sven Erik Gisvold; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; restoration of spontaneous circulation; ROSC; cardiopulmonary resuscitation; CPR; cardiac arrest; methylene blue; MB; S-PBN; mild therapeutic hypothermia; MTH; targeted temperature management; TTM; endothelin; ET-1; ECE-1; ETAR; ETBR; nitric oxide; NO; nitric oxide synthase; NOS; eNOS; iNOS; nNOS; porcine; amiodarone; hypovolemia; milrinone; vasopressin; esmolol; epinephrine; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Medical Cell Biology; Medicinsk cellbiologi; Cardiology; Kardiologi;

    Abstract : It is a major clinical problem that survival rates after out-of-hospital cardiac arrest have not markedly improved during the last decades, despite extensive research and the introduction of new interventions. However, recent studies have demonstrated promising treatments such as targeted temperature management (TTM) and methylene blue (MB). READ MORE

  2. 2. Nitric oxide in brain contusion

    Author : Caroline Gahm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Apoptosis; Colchicine; Dexamethasone; eNOS; human; immunohistochemistry; iNOS; L-NAME; L-NIL; neuronal degeneration; Nimodipine; nitric oxide; NO; nNOS; rat; SPBN; Tirilazad Mesylate; traumatic brain injury;

    Abstract : Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. READ MORE

  3. 3. Nitric oxide in central nervous structures associated with water balance and micturition

    Author : Anders Nylén; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; spinal projections; True Blue; cystometry; circumventricular organs; paraventricular nucleus; supraoptic nucleus; NADPH diaphorase; immunohistochemistry; oxytocin; 8-arginine-vasopressin; hypothalamus; rat; micturition; nitric oxide; water balance; neuronal nitric oxide synthase; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The role of nitric oxide (NO) in the central control of water balance and micturition has not yet been established. In the present thesis, where female rats were used, neuronal NO synthase (nNOS) distribution was studied in structures of the central nervous system known to be associated with the above mentioned control. READ MORE

  4. 4. Macula Densa Derived Nitric Oxide and Kidney Function

    Author : Anna Ollerstam; Pontus Persson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Nitric oxide; rats; kidney; macula densa cells; tubuloglomerular feedback; renin; angiotensin II; blood pressure; hypertension; renal blood flow; neuronal nirtic oxide synthase; Cellbiologi; Cell biology; Cellbiologi; Physiology; fysiologi;

    Abstract : The kidney is the major organ regulating the extracellular fluid volume and thereby the arterial blood pressure. The neuronal isoform of nitric oxide synthase (nNOS) in the kidney is predominantly located in the macula densa cells. READ MORE

  5. 5. Functional Aspects of the Juxtaglomerular Apparatus : Control of Glomerular Filtration and Renin Release

    Author : Johan Sällström; Erik Persson; Peter Hansell; Jürgen Schnermann; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The juxtaglomerular apparatus (JGA) is a control unit of the kidney, that regulates glomerular filtration rate (GFR) and renin release, and hence extracellular volume and blood pressure. The tubuloglomerular feedback (TGF) mechanism is a negative feedback loop that regulates GFR. READ MORE