Search for dissertations about: "nNOS"

Showing result 11 - 15 of 24 swedish dissertations containing the word nNOS.

  2. 11. Nitric oxide, arginine and acute pancreatitis

    Author : Per Sandström; Jörgen Larsson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Acute pancreatitis is a serious inflammatory condition which is managed symptomatically as there is no causal treatment to offer. The main background causes are alcohol abuse and gallstone disease. The inducing factors lead to a premature activation of pancreatic enzymes in the acinar cells and their subsequent release into the pancreatic tissue. READ MORE

  4. 12. Studies on the effect of orexin on upper gastrointestinal function in rats and man

    Author : Marcus Ehrström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Orexin A; orexin receptors; SB-334867-A enteric ganglia; enteroendocrine cells; migrating myoelectric complex; nitric oxide; gastric emptying; gastric acid secretion; leptin; insulin;

    Abstract : Aims: To define the morphological localisation of orexin A (OXA) in the gut, and study the effect of endogenous and peripherally administered OXA on fasting small bowel motility, gastric emptying and acid secretion, hormones involved in glucose homeostasis and pharmacokinetic profile of OXA in rats and humans. Methods: The distribution of OXA, orexin receptors 1 and 2 (OX1 R, OX2R), neuronal nitric oxide synthase (nNOS) and various peptides were studied with immunocytochemistry in rat and human gut. READ MORE

  5. 13. Effects of ethanol on muscarinic acetylcholine receptors in nerve cells

    Author : Murielle Hellsten Caron; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; nerve cell; SH-SY5Y; NOS; PKC; PLC; Ethanol; mAChR;

    Abstract : This thesis focused on the mechanisms involved in the effects of long-term ethanol treatment on mAChRs and their coupled-signal transduction pathway in human neuroblastoma SH-SY5Y cells. All 5 subtypes of mAChRs were expressed in these cells. READ MORE

  6. 14. Nitric oxide synthase in female reproductive and urinary organs: Hormonal regulation and functional significance

    Author : Jassim Al-Hijji; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gynaecology; Obstetrics; estrogen; trophoblast; placenta; vagina; Nitric oxide; uterus; ovarian steroids; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : Nitric oxide synthase (NOS) activity was studied in cytosolic and particulate fractions in reproductive organs from rabbit (uterus and vagina) and rat (uterus, vagina and cervix). NOS was found predominantly in cytosolic fractions in all tissues and the activity of NOS in both fractions was highly Ca2+ dependent. READ MORE

  7. 15. Neuroprotective Effect of Genistein : Studies in Rat Models of Parkinson’s and Alzheimer’s Disease

    Author : Maryam Bagheri; Simin Mohseni; David Engblom; Jan Marcusson; Mark J. West; Linköpings universitet; []
    Keywords : ;

    Abstract : Parkinson’s disease (PD) and Alzheimer’s disease (AD) are neurodegenerative disorders that mainly affect the elderly population. It is believed that oxidative stress is involved in development of both these diseases and that estrogen deficiency is a risk factor for development of AD. READ MORE