Search for dissertations about: "nafld and mice"
Showing result 1 - 5 of 11 swedish dissertations containing the words nafld and mice.
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1. MST3 and MST4: Critical Regulators of Liver Lipid Partitioning and Hepatocarcinogenesis
Abstract : Non-alcoholic fatty liver disease (NAFLD) encompasses a disease spectrum ranging from hepatic steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and finally cirrhosis. With no approved pharmacological treatment, NAFLD is currently the most common etiology of chronic liver disease in Western countries and its prevalence continues to grow. READ MORE
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2. The importance of Cyclophilins and Mps1 in cancer
Abstract : Hepatic fibrosis is a pathological response to chronic liver injuries such as chronic alcohol consumption, non-alcoholic fatty liver disease (NAFLD) or chronic viral infections. No antifibrotic compound has been approved for liver fibrosis and if the cause of the chronic injury is not solved, fibrosis can progress to cirrhosis. READ MORE
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3. Protein kinase STK25 is a regulator of hepatic lipid partitioning and whole body metabolism
Abstract : In past decade, type 2 diabetes (T2D) and associated metabolic complications have become a major global threat for human health with epidemic increase in incidence. Currently available treatments for T2D have several limitations and side effects making it difficult safely reach adequate metabolic control. READ MORE
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4. The role of MBOAT7 on fatty liver disease
Abstract : Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. READ MORE
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5. Microbial modulation of metabolic diseases
Abstract : The gut microbiota, the ensemble of microorganisms living in the gastrointestinal tract, and the host have a mutualist relationship. Alterations of this delicate equilibrium can lead to changes in microbiota composition and/or function leading to the onset of metabolic diseases (e.g., type 2 diabetes and non-alcoholic fatty liver diseases). READ MORE