Search for dissertations about: "nanocarrier"

Found 4 swedish dissertations containing the word nanocarrier.

  2. 1. Drug Delivery to the Brain by Liposomes : Understanding Factors Governing Delivery Outcomes In Vivo

    Author : Yang Hu; Margareta Hammarlund-Udenaes; Teresa Dalla Costa; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nanocarrier; liposome; blood-brain barrier; brain delivery; formulation; methotrexate; diphenhydramine; microdialysis; pharmacokinetics; model-based approach; Farmaceutisk vetenskap; Pharmaceutical Science; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Abstract : The blood-brain barrier (BBB) is the primary obstacle for efficient drug delivery to the central nervous system (CNS). One promising strategy to enhance brain delivery is to utilize nanocarriers (NC), e.g., liposomes, encapsulating CNS drugs. READ MORE

  4. 2. Quantitative Aspects of Nanodelivery Across the Blood-Brain Barrier : Exemplified with the Opioid Peptide DAMGO

    Author : Annika Lindqvist; Margareta Hammarlund-Udenaes; Markus Fridén; William Elmquist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood-brain barrier; liposomes; nanocarriers; brain delivery; pharmacokinetics; modeling and simulation; microdialysis; opioid peptide; DAMGO; LC-MS MS; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : The use of nanocarriers is an intriguing approach in the development of efficacious treatment for brain disorders. The aim of the conducted research was to evaluate and quantify the impact of a liposomal nanocarrier formulation on the brain drug delivery. READ MORE

  5. 3. Hindered diffusion of nanoparticles

    Author : Ananda Subramani Kannan; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Brownian motion; Hydrodynamic interactions; Multiphase DNS; Mobility; Langevin-immersed boundary method; Colloids; Aerosols; Nanoscale and Rarefied gas.;

    Abstract : Brownian theory provides us with a powerful tool which can be used to delve into a microscopic world of molecules, cells and nanoparticles, that was originally presumed to be beyond our reach. Consequently, modeling the inherent dynamics of a system through a Brownian transport equation is of relevance to several real-word problems that involve nanoparticles including, the transport and mitigation of particulate matter (PM) generated though fossil fuel combustion and nanocarrier mediated drug delivery. READ MORE

  6. 4. Engineering Nanotherapeutic Strategies for Osteoarthritis Treatment

    Author : Ula von Mentzer; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanoparticles; nanomedicine; cartilage; osteoarthritis;

    Abstract : Osteoarthritis (OA), the most prevalent joint disorder, is characterized by the degeneration of cartilage tissue leading to pain, stiffness, and impaired mobility. Primarily affecting the elderly, OA can also impact athletes, postmenopausal women, and individuals with conditions like diabetes. READ MORE