Search for dissertations about: "nanodisc"

Showing result 1 - 5 of 6 swedish dissertations containing the word nanodisc.

  2. 1. Plant aquaporin regulation: Structural and functional studies using diffraction and scattering techniques

    Author : Michael Järvå; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray Crystallography; Membrane protein; Plasma membrane intrinsic protein; Aquaporin; pH gating; mercury; proteoliposome assay; water transport; SANS; SAXS; WAXS; nanodisc; liposome;

    Abstract : Water is the basis for life as we know it. It is only logical then that all organisms have evolved specialized proteins, aquaporins, which regulate water flow across their membranes. Plants, which are immobile, depend more on their environment and also use water flows to move, to breathe, and to grow. READ MORE

  4. 2. Structural studies of HDL and applications of EM on membrane proteins

    Author : Lin Zhu; Hans Hebert; Caroline Jegerschöld; Catherine Vénien-Bryan; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; high density lipoprotein; rHDL; apoA-I; transmission electron microscopy; membrane protein; nanodisc; Salipro; transporter; Technology and Health; Teknik och hälsa;

    Abstract : A large number of proteins interact with biological membranes, either integrated in the membrane (PepTSo2), embedded on a membrane surface (5-lipoxygenase) or encircling a cutout of lipid bilayer (apolipoprotein1 (apoA-I). They function as transporters, receptors or biocatalysts in cellular processes like inflammation or cholesterol transport which are touched upon here. READ MORE

  5. 3. Insight into 5-lipoxygenase biocatalysis and interaction with membrane components

    Author : Ramakrishnan B Kumar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Inflammation is one of the innate defence mechanisms exerted by the human body for protection and to initiate the healing process. Chronic inflammatory reactions can lead to several disease conditions like asthma, allergic rhinitis and rheumatoid arthritis. READ MORE

  6. 4. Structure and Function of the Borrelia burgdorferi Porins, P13 and P66

    Author : Mari Bonde; Sven Bergström; Melissa Caimano; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; P13; P66; porin; protein complex; dissemination; osmotic stress;

    Abstract : Borrelia burgdorferi is an elongated and helically shaped bacterium that is the causal agent of the tick-borne illness Lyme disease. The disease manifests with initial flu-like symptoms and, in many cases, the appearance of a skin rash called erythema migrans at the site of the tick bite. READ MORE

  7. 5. Structural Details of Human Aquaporin Regulation : Three stories of three aquaporins

    Author : Veronika Nesverova; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aquaporin; membrane proteins; protein trafficking; water channel; aquaporin 0; aquaporin 5; aquaporin 2; cryo-EM; protein phosphorylation; protein-protein interaction; aquaporin regulation; aquaporins;

    Abstract : Every cell is surrounded by a thin plasma membrane, protecting it from its surrounding. Specialized protein channels and transporters are embedded in this membrane, ensuring selective transport of molecules in and out of the cells. To maintain optimal hydration, water channels called aquaporins (AQPs) are present in every cell of our body. READ MORE