Search for dissertations about: "nanoparticle drug delivery thesis"

Showing result 1 - 5 of 24 swedish dissertations containing the words nanoparticle drug delivery thesis.

2. 1. Multifunctional Glyconanomaterials : Applications in Biorecognition and Drug Delivery

   Author : Zhou Juan; Ramström Olof; Ravin Narain; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; glyconanomaterials; cellulose nanocrystals; chitin nanocrystals; mesoporous silica nanoparticles; lectin; biorecognition; drug delivery; bacteria; cytotoxicity; perfluorophenylazide; fluorescent dye; carbohydrate ligands.;

   Abstract : This thesis consists of three parts, which revolve around the fabrication of multifunctional glyconanomaterials (cellulose nanocrystals, chitin nanocrystals, mesoporous silica nanoparticles) and the development of their applications in biorecognition and nanomedicine.Part one presents a detailed introduction to glyconanomaterials, focusing on cellulose nanocrystals, chitin nanocrystals and mesoporous silica nanoparticles, including their general preparations, properties and applications. READ MORE

4. 2. Study on multifunctional smart drug delivery systems

   Author : Yunsuk Jo; KTH; []
   Keywords : Drug delivery systems; Poly lactic acid ; Poly N-isopropylacrylamide ; Controlled-release; Stimuli-sensitive polymer; Mathematical modeling; Self-assembly; Au nanoparticle; Shell-in-shell structure;

   Abstract : .... READ MORE

5. 3. In vitro characterization of nanodrugs at model lipid membranes

   Author : Rickard Frost; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; in vitro screening; nanomedicine; drug delivery; drug carrier; supported lipid bilayer; QCM-D; nanoparticle; cell membrane;

   Abstract : The use of nano-sized drug carriers to improve the efficiency of drug delivery has become well established during the past decades. New nanoparticle (NP) formulations for the administration of biopharmaceuticals (e.g. proteins and peptides) emerge at an increasing rate and the need for methods to evaluate their properties is expanding. READ MORE

6. 4. Nanoparticle-based drug delivery systems for neural interfaces - a novel approach for improved biocompatibility

   Author : Alexander Dontsios Holmkvist; Neurofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Neural interfaces; brain damage injury; Minocycline; Gelatin; Nanoparticles; Drug-delivery systems; Biocompatibility; Tissue responses; immunohistochemistry IHC ; Poly D; L-lactic-co-glycolic acid PLGA ; Hydrophobic ion paring; Emulsification-solvent-diffusion method; Drug release; Microglia activation;

   Abstract : The overall purpose of this thesis was to reduce brain tissue responses around implanted microelectrodes using a pharmacological strategy. One of the main aims was to develop and evaluate drug delivery systems that allow local administration of anti-inflammatory pharmaceutics. READ MORE

7. 5. Cell-penetrating peptide based nanocomplexes for oligonucleotide delivery

   Author : Jakob Regberg; Ülo Langel; Arwyn Tomos Jones; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; oligonucleotides; gene therapy; drug delivery; scavenger receptors; blood-brain barrier; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Abstract : Oligonucleotide-based drugs hold great promise for the treatment of many types of diseases, ranging from genetic disorders to viral infections and cancer. The problem is that efficient delivery across the cell membrane is required for oligonucleotides to have their desired effect. Cell-penetrating peptides (CPPs) provide a solution to this problem. READ MORE