Search for dissertations about: "nasal gel in thesis"

Showing result 1 - 5 of 7 swedish dissertations containing the words nasal gel in thesis.

  2. 1. Polymer Gels as Pharmaceutical Dosage Forms : Rheological Performance and Physicochemical Interactions at the Gel-Mucus Interface for Formulations Intended for Mucosal Drug Delivery

    Author : Helene Hägerström; Katarina Edsman; Arne Brodin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; gel; rheology; mucoadhesion; mucosal drug delivery; in situ gel; gellan gum; Carbopol; tensile strength; nasal mucosa; intranasal administration; dielectric spectroscopy; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Abstract : Drug delivery to the nasal and ocular mucosa faces several obstacles. One of these is from the effective clearance mechanisms present in the nose and eye. Polymer gels with suitable rheological properties can facilitate the absorption of poorly absorbed drugs by increasing the contact time of the drug with the mucosa. READ MORE

  4. 2. Topical formulations, design and drug delivery : "A dive into water"

    Author : Abdullah Ali; Marie Lodén; Anan Yagmur; Anders Hall; Malmö universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; water; topical formulations; Pickering emulsion; skin cream; drug delivery; tactile friction; sensory panel; nasal; buccal; mucosa; skin; triglycerides; ethanol; drug transport; cosmetic appeal;

    Abstract : Water is a vital component regulating the properties of topical formulations and their interaction with biological barriers, such as skin and mucosa. Changing the watercontent within the frame of the pharmaceutical triangle will have a huge impact on which type of formulation, such as a cream, ointment, gel, or lotion, is formed, as well as the physical properties of the formulation. READ MORE

  5. 3. Controlled Release Gel Formulations for Mucosal Drug Delivery

    Author : Mattias Paulsson; David Attwood; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; Galenisk farmaci; Pharmaceutics;

    Abstract : Drug delivery to nasal or ocular mucosa for either local or systemic action faces many obstacles – these routes are protected by effective mechanisms. Gel formulations with suitable rheological and mucoadhesive properties increase the contact time at the site of absorption. READ MORE

  6. 4. New Mediators and Novel Mechanisms in Allergic Airway Inflammation

    Author : Malin Bryborn; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic airway inflammation; airway hyperreactivity; inflammatory mediators; S100A7; IL-4; proteomics; genetic variation; Charcot-Leyden crystal protein;

    Abstract : Hyperresponsiveness and inflammation are major pathophysiological features of both allergic rhinitis and asthma. The mechanisms behind these are not fully understood. READ MORE

  7. 5. Nasopharynx and mucosa associated lymphatic tissue : studies on mucosal immunity, nasopharyngeal colonization with non-encapsulated non-typable Haemophilus influenzae and local administration of immunoglobulin in the upper respiratory tract

    Author : Karin Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nasopharyngeal colonization with non-encapsulated Haemophilus influenzae (NTHI) frequently occurs in infants and in adults with common variable immunodeficiency (CVID), but is rarely found among healthy adults. In children with recurrent episodes of acute otitis media (RAOM), NTHI is more common than in healthy individuals. READ MORE