Search for dissertations about: "natural cytotoxicity"

Showing result 1 - 5 of 102 swedish dissertations containing the words natural cytotoxicity.

  1. 1. Biologically Interesting Compounds from Natural Sources

    Author : Veronica de la Parra; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cytotoxicity; Natural products; terpenoids; vasorelaxant activity; allylmercaptane; diabetes mellitus type II; Organisk kemi; Organic chemistry; Cacalia decomposita; GPR40 receptor; TRP channel;

    Abstract : Natural products have traditionally played a major role in the drug discovery process. Besides constituting extremely popular drugs in the market, and an ever-increasing source of interesting and novel chemical structures, they have also aided the characterization of many a pharmacological target. READ MORE

  2. 2. Structural studies of heterogeneous amyloid species of lysozymes and de novo protein albebetin and their cytotoxicity

    Author : Vladimir Zamotin; Ludmilla Morozova-Roche; Daniel Otzen; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; amyloid; cytotoxicity; atomic force microscopy; Biophysics; Biofysik;

    Abstract : A number of diseases are linked to protein folding problems which lead to the deposition of insoluble protein plaques in the brain or other organs. These diseases include prion diseases such as Creutzfeld-Jakob disease, Alzheimer's disease, Parkinson's disease and type II (non-insulin dependent) diabetes. READ MORE

  3. 3. Antiparasitic metabolites from plants used in the Tacana Bolivian native tribe : Traditional medicine, an overview of natural products with medicinal interest

    Author : Ivan Limachi; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Tacana Traditional Medicine; Antiparasitic; cytotoxicity; Hyptis brevipes; hyptis mutabilis; Tessaria integrifolia; Trichilia adolfi;

    Abstract : The thesis aims to contribute to the preservation of traditional medicinal knowledge of the Tacana Bolivian native tribe, as well as to the isolation and characterization of antiparasitic metabolites from plants used for the treatment of endemic diseases. A selection of medicinal plants, made in collaboration with the Tacana communities who decided which plants have a specific medicinal propose, were collected and identified by the national herbarium of Bolivia, and confirmed by healers from the most representative communities. READ MORE

  4. 4. Synthesis of Bioactive Analogues of Marasmane Dialdehydes

    Author : Daniel Röme; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; Cancer; Enantioselective synthesis; Totalsynthesis; Semisynthesis; Cytotoxicity; Anti-tumor activity; Isovelleraloids; Marasmic acid; Marasmane dialdehydes; Isovelleral;

    Abstract : The modification of drugs into pro-drugs is an attractive concept allowing you to tweak the chemical and physical properties of a drug without changing the original structure of the active compound. In principle, any compound possessing a preferred biological activity can be transformed into a pro-drug. READ MORE

  5. 5. Nanoparticles for multifunctional drug delivery systems

    Author : Jian Qin; Mamoun Muhammed; Paavo K J Kinnunen; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; drug delivery; stimuli-sensitive; SPION; PLLA; PNIPAAm; gold; MRI; cytotoxicity; Pluronic; phase transfer; Materials chemistry; Materialkemi;

    Abstract : Multifunctional drug delivery systems incorporated with stimuli-sensitive drug release, magnetic nanoparticles and magnetic resonance (MR) T2 contrast agents is attracting increasing attention recently. In this thesis, works on polymer nanospheres response to temperature change, superparamagnetic iron oxide nanoparticles (SPION)/polymeric composite materials for MR imaging contrast agents are summarized. READ MORE