Search for dissertations about: "necrotic"

Showing result 11 - 15 of 97 swedish dissertations containing the word necrotic.

  2. 11. The role of the mitochondrion in organotin-induced T-cell apoptosis

    Author : Hélène Stridh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Apoptosis plays a central role in the development and the function of the immune system. The cell death program can, however, be inappropriately activated or suppressed under pathological conditions. Several toxins have been shown to interfere with intra-thymic processes, thereby contributing to autoimmune disorders. READ MORE

  4. 12. Cell damage and tissue repair in the central nervous system : electron mi[c]roscopy study of neuronal death and cell replacement

    Author : Benita Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ischemia; cell death; repair; stem cells; neurogenesis; EM; MRI;

    Abstract : The central nervous system is vulnerable to various insults and particularly to ischemia. To mimic ischemia, a photochemical or compression lesion was induced in the right sensory motor cortex of rat brains. READ MORE

  5. 13. T-cell specificity and regulation in atherosclerosis

    Author : Anton Gisterå; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived macrophages and T-helper (Th) 1 cells to form lipid-laden atherosclerotic plaques in the artery wall. READ MORE

  6. 14. Human cytokeratins : their use as targets in cancer management

    Author : Birgitta Sundström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cytokeratins, biochemically related to intermediate filaments (IF), form an intracellular network of filaments which contributes to the mechanical stabilizing of the cell. 19 individual polypeptides, divided into two groups, constitute the cytokeratin family. READ MORE

  7. 15. Aspects of pathological apoptosis in the immature brain after hypoxia-ischemia

    Author : Ulrika Hallin; Göteborgs universitet; []
    Keywords : neonatal; rat; brain; hypoxia-ischemia; necrosis; apoptosis; calpain; caspase; Bcl-2; Bax; mitochondria; calcineurin.;

    Abstract : The cause of mechanisms underlying perinatal brain injury is not fully known, but it results in a wide variety of neurological impairments in the affected children. When injured, neurons of the newborn brain are prone to undergo programmed cell death, apoptosis, since this genetic program is normally activated in some cells during development of the nervous system, even in the perinatal period. READ MORE