Search for dissertations about: "nefrologi"

Showing result 16 - 20 of 28 swedish dissertations containing the word nefrologi.

  1. 16. INVASIVE BLADDER CANCER - Aspects on staging and prognosis

    Author : Fredrik Liedberg; Urologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urology; prognosis; invasive bladder cancer; staging; Urologi; nefrologi;

    Abstract : Background: The difficulty of determining the prognosis for the individual patient with invasive bladder cancer is a major clinical problem. Currently, decisions regarding therapy are mainly based on tumour stage and grade, the first of which is notoriously demanding to ascertain. READ MORE

  2. 17. MOLECULAR PROFILING OF UROTHELIAL CARCINOMA

    Author : David Lindgren; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytogenetik; Urology; nephrology; Urologi; nefrologi; Clinical genetics; Klinisk genetik; cytogenetics; Genetics; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; TP53; FGFR3; gene expression profiling; microarray; bladder cancer; urothelial carcinoma; Genetik;

    Abstract : The general aim of this thesis was to molecularly characterize urothelial carcinoma (UC) at the transcriptional level using gene expression microarrays to improve the classification and pathogenetic understanding of this disease. In the first two studies (Articles I and II), gene expression profiling was used to study dysregulated transcriptional networks in a large cohort of UCs. READ MORE

  3. 18. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura

    Author : Minola Manea Hedström; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; tubular cells; podocytes; kidney; plasma; ADAMTS13; thrombotic thrombocytopenic purpura; nephrology; Urologi; nefrologi; Pediatrics; Pediatri;

    Abstract : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. READ MORE

  4. 19. The patient with bladder cancer. From symptoms, through treatment, with special reference to psychosocial consequences of radical cystectomy

    Author : Åsa G E Månsson; Urologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; philosophical attitudes; psychosocial intervention; projective test; postoperative adjustment; Bladder cancer; cystectomy; quality of life; Urology; nephrology; Urologi; nefrologi;

    Abstract : Factors determining patient`s and doctor`s delay in diagnosis of bladder cancer were type of initial symptoms, level of health service first consulted and number of steps in the referral system. No correlation was found between psychosocial factors and patient`s delay. READ MORE

  5. 20. The Balance between Pro- and Antiinflammatory Molecules in ANCA-Associated Vasculitis

    Author : Sophie Ohlsson; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urologi; nefrologi; Urology; monocyte; SLPI; proteinase 3; ANCA; vasculitis; inflammation;

    Abstract : ANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). READ MORE