Search for dissertations about: "negative selection"
Showing result 1 - 5 of 296 swedish dissertations containing the words negative selection.
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1. Robust inference of gene regulatory networks : System properties, variable selection, subnetworks, and design of experiments
Abstract : In this thesis, inference of biological networks from in vivo data generated by perturbation experiments is considered, i.e. deduction of causal interactions that exist among the observed variables. Knowledge of such regulatory influences is essential in biology. READ MORE
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2. Tracing selection and adaptation along an environmental gradient in Populus tremula
Abstract : The distribution of the expressed genotype is moved around in the population over time byevolution. Natural selection is one of the forces that act on the phenotype to change the patterns ofnucleotide variation underlying those distributions. READ MORE
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3. Evolutionary consequences of sex-specific selection
Abstract : Sex-specific selection is widespread, evident by the evolution of sexual dimorphism in many traits in sexually reproducing taxa. The reason why the sexes may experience selection that differs in direction or magnitude is often linked to the reproductive strategies associated with the sex-specific reproductive physiology. READ MORE
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4. Population genomic analyses of regulatory variation and selection in Brassicaceae species
Abstract : The impact of selection on regulatory variation and the contribution of regulatory changes to phenotypic variation has long been debated in evolutionary genetics. Because cis-regulatory elements such as promoters and enhancers can be difficult to identify, it has been more challenging to quantify the impact of selection on variation in cis-regulatory regions than in protein-coding regions. READ MORE
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5. Biological and Pharmacological Factor that Influence the Selection of Antibiotic Resistance
Abstract : Antibiotic treatment causes an ecological disturbance on the human microflora. Four commensal bacteria: E. coli, enterococci, a-streptococci and coagulase-negative staphylococci, from patients with extensive, high antibiotic usage were investigated with regard to resistance pattern and mutation frequency. READ MORE