Search for dissertations about: "neglected tropical diseases"

Showing result 1 - 5 of 8 swedish dissertations containing the words neglected tropical diseases.

  2. 1. Accelerating the discovery of drugs for Neglected Tropical Diseases using biophysical methods

    Author : Giulia Opassi; Helena Danielson; Jenny Sandmark; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neglected Tropical Diseases; Drug Discovery; Biochemistry; Biophysics; Kinetic; Fragment Based Lead Discovery; Assay Development;

    Abstract : Even though they account for 10% of the global disease burden and besides the new record of funding in 2018, tropical diseases are still neglected by the majority of pharmaceutical companies and public funding. The reason can be mostly found in the fact that for these diseases a conventional drug discovery process is often too expensive. READ MORE

  4. 2. It is on my skin, on my soul, and on my life : development of a disease-specific quality of life instrument for adult patients with acute cutaneous leishmaniasis in Iran

    Author : Alireza Khatami; Berndt Stenberg; Maria Emmelin; Hans Stenlund; Farhad Handjani; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cutaneous leishmaniasis; fundamental measurement; needs-based approach; neglected tropical disease; probabilistic model; quality of life; qualitative content analysis; the Rasch model; epidemiologi; Epidemiology;

    Abstract : Background: Cutaneous leishmaniasis (CL), is the most common form of a group of diseases known as leishmaniases. They are caused by obligatory intracellular protozoa from the genus Leishmania and transmitted by sandflies. READ MORE

  5. 3. Pharmacovigilance capacity in East Africa with focus on neglected tropical diseases

    Author : Abbie Barry; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pharmacovigilance aims to enhance patient safety in relation to the use of medicines by reducing the incidence and severity of adverse events which includes supporting public health programs by providing information on the safety profile of medicines used by the programs. In Africa, the increased access to medicinal products is not well-matched with the pharmacovigilance capacity to monitor drug safety. READ MORE

  6. 4. Control or elimination : terms for public health interventions against tungiasis and schistosomiasis haematobium

    Author : Per Nordin; Ingela Krantz; Stig Wall; Andreas Ruppel; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tungiasis; urogenital schistosomiasis; control; elimination; public health; intervention; diagnosis; treatment; neglected tropical diseases; praziquantel; mass treatment; Public health; folkhälsa;

    Abstract : The thesis revolves around diagnosis and treatment of tungiasis (sand flea disease) and schistosomiasis haematobium. The causing parasites, Tunga penetrans and Schistosoma haematobium, both have the ability to penetrate intact skin. READ MORE

  7. 5. Oral eflornithine treatment of late-stage human African trypanosomiasis

    Author : Mikael Boberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sleeping Sickness; Neglected Tropical Diseases; Enantiomers; Nonlinear Mixed Effects Modeling; Pharmacokinetics; Pharmacodynamics;

    Abstract : Human African trypanosomiasis is a fatal disease unless treated. It is a parasitic vector borne disease endemic in sub-Saharan African countries. Eflornithine is a recommended treatment for gambiense human African trypanosomiasis (g-HAT) in the later disease stage when the parasites have infected the central nervous system. READ MORE