Search for dissertations about: "neo-adjuvant androgen deprivation"

Found 2 swedish dissertations containing the words neo-adjuvant androgen deprivation.

  2. 1. Neoadjuvant hormone treatment in localized prostate cancer : a clinical and histopathological study

    Author : Magnus Hellström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Localized prostate cancer; radical prostatectomy; neo-adjuvant androgen deprivation; GnRH-agonist; histopathology; immunohistochemistry; image analysis; cancer volume; DNA ploidy patterns; PSA in serum; follow-up; prognosisStockholm 1996;

    Abstract : Surgical treatment of localized prostate cancer may be hampered by the spread of cancer through the prostate capsule and in the surgical margins. The prostate is dependent on androgen hormones for its growth and function. READ MORE

  4. 2. Study of the mechanisms behind the additive effect of neoadjuvant castration on radiotherapy for prostate cancer

    Author : Firas L Tarish; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Castration improves responses to radiotherapy (RT) in prostate cancer with unknown mechanism. An understanding of what happens at the cellular and molecular level in prostate cancer cells, while reducing their access to androgens and then exposing them to ionizing radiation (IR), would give us an opportunity to optimize the treatment and may also inspire novel therapeutic approaches. READ MORE