Search for dissertations about: "neonatal brain injury"

Showing result 6 - 10 of 39 swedish dissertations containing the words neonatal brain injury.

  2. 6. Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries

    Author : E. Axel Andersson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neonatal brain injury; hypoxia ischemia; germinal matrix haemorrhage; blood brain barrier; tight‐junctions; blood vessels;

    Abstract : Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can irreversibly injure the brain, but clinical tools for diagnosing and treating these pathologies are lacking. READ MORE

  4. 7. The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury

    Author : Maria Hammarlund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha 7 nicotinic acetylcholine receptor; inflammation; brain injury; CHRNA7; CHRFAM7A; stroke; hypoxia ischemia; neonatal encephalopathy; human; PBMC;

    Abstract : The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common component in the pathology of many diseases and injuries, including brain damage. READ MORE

  5. 8. Hypoxic-ischemic injury in the immature brain. Role of mitochondria, caspases and NMDA receptors

    Author : Malgorzata Puka-Sundvall; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neonatal; immature rats; hypoxia-ischemia; brain damage; calcium; mitochondria; permeability transition; apoptosis; caspase-3; NMDA receptor; electron microscopy;

    Abstract : .... READ MORE

  6. 9. Inflammation and neuroprotective strategies in the immature brain after hypoxic-ischemic brain injury

    Author : Pernilla Svedin; Göteborgs universitet; []
    Keywords : hypoxia-ischemia; LPS; immature; brain; inflammation; NAC; melatonin; G-2mPE; MMP-9; MMP-12;

    Abstract : Perinatal brain injury, as a result of hypoxia-ischemia (HI) or infection/HI, is a major cause of acute mortality and neurological morbidity in infants and children. The mechanisms of perinatal HI are not fully understood, which makes it difficult to find effective treatment. READ MORE

  7. 10. Characterization of immune cell profiles in meninges and brain parenchyma following injury in the developing mouse brain

    Author : Aura Zelco; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preterm brain injury; hypoxia-ischemia; immune response; neonatal meninges;

    Abstract : Preterm newborns are particularly susceptible to complications such as hypoxia-ischemia (HI), which can result in brain injury and subsequent cognitive and/or motor function disabilities, including cerebral palsy. Immune cells have been shown to be involved in the development of perinatal brain damage, commonly with detrimental effects. READ MORE