Search for dissertations about: "network biology"

Showing result 1 - 5 of 291 swedish dissertations containing the words network biology.

  1. 1. Genetic mechanisms regulating proliferation and cell specification in the Drosophila embryonic CNS

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Shahrzad Bahrampour; Linköpings universitet.; Linköpings universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The central nervous system (CNS) consists of an enormous number of cells, and large cellular variance, integrated into an elaborate network. The CNS is the most complex animal organ, and therefore its establishment must be controlled by many different genetic programs. READ MORE

  2. 2. Systems Biology of Yeast Lipid Metabolism

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Pramote Chumnanpuen; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Transcriptome; Integrated analysis; Lipidome.; Inositol-choline; Opi1; Yeast lipid metabolism; high throughput techniques; Ino4; TORC1; Snf1; Ino2;

    Abstract : Lipid metabolism plays an important role in the development of many different life-style related diseases, such as type 2 diabetes and atherosclerosis, and understanding the molecular mechanisms behind regulation of lipid biosynthesis and degradation may lead to development of new therapies. In this project we undertook a global study of lipid metabolism in the eukaryotic model organism Saccharomyces cerevisiae. READ MORE

  3. 3. Network and gene expression analyses for understanding protein function

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Oliver Frings; Stockholms universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biological networks; network inference; network analysis; clustering; network module; network crosstalk; expression analysis; gene signature; biomarker; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Abstract : Biological function is the result of a complex network of functional associations between genes or their products. Modeling the dynamics underlying biological networks is one of the big challenges in bioinformatics. READ MORE

  4. 4. Functional association networks for disease gene prediction

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Dimitri Guala; Stockholms universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. READ MORE

  5. 5. Characterization of New Players in Planar Polarity Establishment in Arabidopsis

    University dissertation from Umeå : Umeå University

    Author : Stefano Pietra; Umeå universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SABRE; planar polarity; CLASP; cell division orientation; microtubule cytoskeleton; actin; AIP1; patterning; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Abstract : Coordinated polarity and differentiation of cells in the plane of a tissue layer are essential to the development of multicellular organisms. Arabidopsis thaliana root hairs and trichomes provide model systems to study the pathways that control planar polarity and cell fate specification in plants. READ MORE