Search for dissertations about: "neural crest stem cells"

Showing result 1 - 5 of 26 swedish dissertations containing the words neural crest stem cells.

  2. 1. The beneficial Effects of Neural Crest Stem Cells on Pancreatic      β–cells

    Author : Anongnad Ngamjariyawat; Elena Kozlova; Leif Jansson; Jens Nielsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural Crest Stem Cells; Pancreatic Islets; β-cell proliferation; β-cell survival; Cadherin; Medical Science; Medicinsk vetenskap;

    Abstract : Patients with type-1 diabetes lose their β-cells after autoimmune attack. Islet transplantation is a co-option for curing this disease, but survival of transplanted islets is poor. Thus, methods to enhance β-cell viability and function as well as methods to expand β-cell mass are required. READ MORE

  4. 2. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans

    Author : Liza Grapensparr; Per-Ola Carlsson; Leif Jansson; Mia Phillipson; Aileen King; Uppsala universitet; []
    Keywords : Islets of Langerhans; beta cells; diabetes; transplantation; vascularization; Schwann cells; endothelial progenitor cells; neural crest stem cells; Medicinsk vetenskap; Medical Science;

    Abstract : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. READ MORE

  5. 3. Neural stam cells, TLX, and Neuroblastoma

    Author : Ravi Kanth Rao Saini; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; TLX; Neural Stem Cells; Dedifferentiation; DISC-1; DNA-PKcs;

    Abstract : Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of NB has been linked to the neural crest derived sympathoadrenal progenitor cells. READ MORE

  6. 4. Neuroprotection in the Injured Spinal Cord : Novel Strategies using Immunomodulation, Stem cell Transplantation and Hyaluronic acid Hydrogel carriers

    Author : Nikos Schizas; Nils Hailer; Elena Kozlova; Mikael Svensson; Uppsala universitet; []
    Keywords : Hyaluronic Acid-based hydrogel; motorneurons; microglial cells; Interleukin-1 Receptor Antagonist; Renshaw cells; excitotoxicity; neuroinflammation; Neural Crest Stem Cells; Medicinsk vetenskap; Medical Science;

    Abstract : The overall aim of this thesis was to establish strategies to minimize secondary damage to the injured spinal cord. Secondary damage that follows spinal cord injury (SCI) involves inflammatory and excitotoxic pathways. READ MORE

  7. 5. Sensory neurons : stem cells and development

    Author : Jens Hjerling-Leffler; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sensory neuron; stem cells; development; boundary cap; GABA; TRPV 1; TRPA 1; TRPM8; calcium imaging; Foxs 1; SSEA-1; Schwann cells;

    Abstract : The sensory nervous system is the only means we have of communicating with the surrounding world. The neurons responsible for the sensation of pain, touch, the ability to know the position of our limbs and part of maintenance of body posture are located in the dorsal root ganglia (DRG). READ MORE