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Showing result 1 - 5 of 10 swedish dissertations matching the above criteria.
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1. Merging electronics and the brain - towards a fully biocompatible neural interface
Abstract : Techniques for interfacing the nervous system using chronically implanted electrodes are turning into invaluable tools for neurophysiological research and treatment of neurological disorders. These methods have been developed and refined over the last decades. READ MORE
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2. Silicon neural interfaces -Design and biomedical aspects-
Abstract : This thesis covers the development of a silicon neural interface, with focus on silicon sieve electrode fabrication, design, nerve regeneration, signal recording and biocompatibility. A study of how the via hole size and transparency of the perforated sieve membrane influences the nerve regeneration is presented together with a study on soft tissue responses to planar and porous silicon. READ MORE
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3. Strategies in Cochlear Nerve Regeneration, Guidance and Protection : Prospects for Future Cochlear Implants
Abstract : Today, it is possible to restore hearing in congenitally deaf children and severely hearing-impaired adults through cochlear implants (CIs). A CI consists of an external sound processor that provides acoustically induced signals to an internal receiver. READ MORE
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4. Nanoparticle-based drug delivery systems for neural interfaces - a novel approach for improved biocompatibility
Abstract : The overall purpose of this thesis was to reduce brain tissue responses around implanted microelectrodes using a pharmacological strategy. One of the main aims was to develop and evaluate drug delivery systems that allow local administration of anti-inflammatory pharmaceutics. READ MORE
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5. X-ray and neutron μCT of biomedical samples: from image acquisition to quantification
Abstract : Even though the validity of x-ray computed tomography in the analysis of biomedical samples is nowadays undisputed, the more recent imaging techniques and more advanced instruments (such as synchrotrons) are still relatively unknown to many medical doctors that could benefit from them.The doctoral work presented in this thesis joins a collective effort from the imaging community to demonstrate potential applications of advanced x-ray and neutron imaging methods to preclinical medical research, with the hope of contributing to reach a “critical mass” in the medical community and in the public opinion as well. READ MORE