Search for dissertations about: "neuraminidase inhibitor"

Found 2 swedish dissertations containing the words neuraminidase inhibitor.

  2. 1. Prescription – Pollution – Poo – Pandemics - Priorities : Neuraminidase Inhibitors from an Environmental Resistance Development Perspective

    Author : Marie Nykvist; Josef D. Järhult; Mikael Leijon; Uppsala universitet; []
    Keywords : Influenza A virus; neuraminidase inhibitor; resistance; environmental; Mallard; zanamivir; avian influenza;

    Abstract : The natural Influenza A virus (IAV) host is waterfowl. Human IAV is treated with neuraminidase inhibitors (NAIs), which are stockpiled worldwide in case of an IAV pandemic. As the drugs escape regular waste water treatment, they can be detected in river waters. READ MORE

  4. 2. Resistance to neuraminidase inhibitors in influenza A virus isolated from mallards

    Author : Goran Orozovic; Björn Olsen; Johan Lennerstrand; Sigvard Olofsson; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; influenza; mallards; neuraminidase; PCR; sequencing; mutation; oseltamivir; zanamivir; resistance; NAI; antivirals; pandemic; Virology; Virologi; Molecular biology; Molekylärbiologi; Bioinformatics; Bioinformatik; Zoonotisk ekologi; Zoonotic Ecology; Virology; Virologi; Biokemi; Biochemistry;

    Abstract : Influenza A virus belongs to the Orothomyxoviridae family of viruses and is one of the most common pathogens that cause infections of the respiratory tract. The aim of this thesis was to investigate if neuraminidase inhibitor (NAI) Tamiflu® (oseltamivir, OC) and Relenza® (zanamivir, ZA) - related resistance mutations exist in the neuraminidase (NA) gene of viruses collected from wild birds. READ MORE