Search for dissertations about: "neurodegeneration"

Showing result 11 - 15 of 226 swedish dissertations containing the word neurodegeneration.

  1. 11. Biomarkers in Multiple Sclerosis - Monitoring disease activity and treatment afficacy

    Author : Lenka Nováková Nyrén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; multiple sclerosis; neurodegeneration; inflammation; treatment;

    Abstract : The pathophysiology of multiple sclerosis (MS) is complex with the presence of inflammation and neurodegeneration in all stages of the disease. The disease course, treatment response and outcome are highly variable in MS. READ MORE

  2. 12. Transmethylation, Polyamines and Apoptosis in Amyotrophic Lateral Sclerosis

    Author : Titti Ekegren; Håkan Askmark; Cecilia Gomes-Trolin; Sten-Magnus Aquilonius; Christopher Fowler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; amyotrophic lateral sclerosis; neurodegeneration; transmethylation; polyamine; apoptosis; Neurovetenskap; Neurology; Neurologi;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive disorder characterized by degeneration of motor neurons in the cortex, brainstem and spinal cord. The patients usually die within 3-5 years after onset. The full etiology of ALS is unknown and many hypotheses have been proposed to explain the neurodegeneration. READ MORE

  3. 13. lnduction Therapies in Multiple Sclerosis - Clinical and immunological follow-up

    Author : Sofia Sandgren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple Sclerosis; Neurodegeneration; Alemtuzumab; Autologous hematopoietic stem cell transplantation; Induction therapies Immune reconstitution therapies;

    Abstract : Multiple sclerosis (MS) is a chronic disease that damages the central nervous system. Its pathophysiology is complex, and consists of inflammation and degeneration from the disease onset. The treatment of MS has continuously been developed with improved efficacy. READ MORE

  4. 14. Methods for the analysis and characterization of brain morphology from MRI images

    Author : Irene Brusini; Chunliang Wang; Örjan Smedby; Eric Westman; Lars-Olof Wahlund; Jorge Cardoso; KTH; Karolinska Institutet; Karolinska Institutet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain MRI; Image Segmentation; Machine Learning; Deep Learning; Shape Analysis; Aging; Neurodegeneration; MRT av hjärnan; Bildsegmentering; Maskininlärning; Djupinlärning; Formanalys; Åldrande; Neurodegeneration; Medical Technology; Medicinsk teknologi;

    Abstract : Brain magnetic resonance imaging (MRI) is an imaging modality that produces detailed images of the brain without using any ionizing radiation. From a structural MRI scan, it is possible to extract morphological properties of different brain regions, such as their volume and shape. READ MORE

  5. 15. Computational Approaches to the Degeneration of Brain Networks and Other Complex Networks

    Author : Simachew Abebe Mengiste; Jeanette Hällgren Kotaleski; Arvind Kumar; Ad Aertsen; Michelle Rudolph; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurodegeneration; Synaptic pruning; Networks; Structure; Dynamics; Controllability;

    Abstract : Networks are ubiquitous with several levels of complexity, configuration, hierarchy and function. Many micro- and macro-scale biological or non-biological interactions define complex systems. READ MORE