Search for dissertations about: "neurodevelopment"

Showing result 21 - 25 of 53 swedish dissertations containing the word neurodevelopment.

  2. 21. Pregnancy in Ro/SSA positive women

    Author : Joanna Tingström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Congenital heart block (CHB) may develop in the fetus during pregnancy in Ro/SSA positive women. It is a rare but life-threatening disease and the most serious manifestation of neonatal lupus erythematosus (NLE). The frequency of CHB in Ro/SSA autoantibody positive pregnancy is 1-2%, with a recurrence rate of 12-17%. READ MORE

  4. 22. Single cell analysis of iPS derived neural stem cells and neurons

    Author : Matti Lam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In vitro derived neural stem cells can be used to model events of neurogenesis and neurodevelopmental dysfunction. Formation of stable neural stem cell environments relies on cellular components to stabilize cell-to-cell connections. READ MORE

  5. 23. Physiological consequences of Elongator complex inactivation in Eukaryotes

    Author : Tony Karlsborn; Anders Byström; Hans Ronne; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Elongator complex; wobble uridine modifications; IKBKAP; IKAP; Familial dysautonomia; Untargeted Metabolic profiling.; molekylärbiologi; Molecular Biology;

    Abstract : Mutations found in genes encoding human Elongator complex subunits have been linked to neurodevelopmental disorders such as familial dysautonomia (FD), rolandic epilepsy and amyotrophic lateral sclerosis. In addition, loss-of-function mutations in genes encoding Elongator complex subunits cause defects in neurodevelopment and reduced neuronal function in both mice and nematodes. READ MORE

  6. 24. Ultrasound-guided in utero lentivirus transduction of the murine nervous system to investigate nervous system disorders

    Author : Katrin Mangold; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neurodevelopment is a highly dynamic process involving hundreds of molecular different cell types. Gain and loss of function studies provide valuable insight into the gene regulatory networks that orchestrate this morphological process. READ MORE

  7. 25. Early identification of motor problems in very preterm infants : An evaluation of the Structured Observation of Motor Performance in Infants

    Author : Cecilia Montgomery; Lena Hellström-Westas; Kristina Persson; Katarina Strand Brodd; Ann-Christin Eliasson; Uppsala universitet; []
    Keywords : motor performance; very preterm infants; movement quality; motor competence; radiology; Physiotherapy; Sjukgymnastik fysioterapi;

    Abstract : Infants born very preterm are at risk of adverse neurodevelopment. It is important to identify motor problems early to initiate interventions aiming at ameliorating outcomes. Evaluating motor development in high-risk infants is a complex task. There is a need for assessment methods for early identification of abnormal motor performance. READ MORE