Search for dissertations about: "neurogenesis"

Showing result 16 - 20 of 169 swedish dissertations containing the word neurogenesis.

  1. 16. Differential effects of voluntary running on hippocampal plasticity in the adult rat brain

    Author : Andrew Stuart Naylor; Göteborgs universitet; []
    Keywords : exercise; hippocampus; stress; progenitor proliferation; neurogenesis; trophic factors; frontal cortex; spatial memory; rat; pCREB; endogenous opioids;

    Abstract : The continuation of neuronal birth from dividing neural stem cells in the dentate gyrus of the hippocampus throughout adulthood is known to play an important role in maintaining normal hippocampal function, such as memory and learning. Negative alterations in the levels of adult neurogenesis have also been linked to several neurodegenerative diseases, including Alzheimer s disease and mood disorders such as depression. READ MORE

  2. 17. Brain-derived neurotrophic factor in cerebral ischemia: a quantitative study on surviving and newly formed neurons

    Author : Elin Gustafsson; Lund Klinisk fysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain-derived neurotrophic factor; cerebral ischemia; neuronal survival; neurogenesis; hippocampus; striatum; immunocytochemistry; stereology; neuropsykologi; Neurologi; neurophysiology; neuropsychology; neurofysiologi; Neurology;

    Abstract : This study explores the role of brain-derived neurotrophic factor (BDNF) for neuronal vulnerability and neurogenesis following cerebral ischemia in the rat. Cerebral ischemia results in selective neuronal cell loss in specific brain regions. We here demonstrate the rank order of vulnerability in two regions affected by global forebrain ischemia, i. READ MORE

  3. 18. Brain Regeneration - in vitro and in vivo studies of exercise-related effects on brain plasticity

    Author : Cecilia Bull; Göteborgs universitet; []
    Keywords : brain; neural progenitor cells; stem cells; hippocampus; corpus collosum; rat; mouse; regeneration; neurogenesis; oligodendrogenesis; irradiation; exercise;

    Abstract : Neural stem and progenitor cells in the germinal regions of the adult brain, such as the hippocampus, are of great interest, because they provide the possibility for enhanced brain plasticity or can contribute to endogenous cell replacement after injury or disease. Voluntary exercise was recently shown to robustly induce cellular and structural plasticity, thereby contributing to overall brain health. READ MORE

  4. 19. Neurogenic and inflammatory response in the rodent brain following stroke

    Author : Ursula Heldmann; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; Mac-1-saporin; TNF-a; Neurogenesis; Microglia; stroke; aging;

    Abstract : Stroke and in this case cerebral infarction affects 20 million people each year and five million of them die. In Sweden 30-35000 people will be affected and one of three of them will be severely disabled. In addition, one of six will suffer a new stroke within six years. READ MORE

  5. 20. Vitamin A regulated neuronal regeneration and homeostasis

    Author : Sofia Håglin; Anna Berghard; Staffan Bohm; Leif Carlsson; Ola Hermanson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Activity dependent; Adult stem cells; Ageing; CYP26B1; Homeostasis; Metaplasia; Neurogenesis; Olfactory epithelium; Regeneration; Respiratory epithelium; Retinoic acid; Sensory map; Vitamin A;

    Abstract : The olfactory epithelium is a dynamic tissue maintained by continuous neurogenesis throughout life. Upon injury, neurons and other olfactory cell types are regenerated through proliferation of horizontal stem cells. Some genes that regulate vitamin A metabolism are spatially expressed in the olfactory epithelium. READ MORE