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Showing result 1 - 5 of 97 swedish dissertations matching the above criteria.

2. 1. Clinical Consequences of Axonal Injury in Traumatic Brain Injury

   Author : Sami Abu Hamdeh; Niklas Marklund; Per Enblad; Lars Hillered; Andreas PhD Unterberg MD; Uppsala universitet; []
   Keywords : Traumatic brain injury; diffuse axonal injury; intracranial pressure; magnetic resonance imaging; amyloid-beta; tau; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI), mainly caused by road-traffic accidents and falls, is a leading cause of mortality. Survivors often display debilitating motor, sensory and cognitive symptoms, leading to reduced quality of life and a profound economic burden to society. READ MORE

4. 2. Cellular Reactions and Behavioral Changes in Focal and Diffuse Traumatic Brain Injury : A Study in the Rat and Mouse

   Author : Sara Ekmark Lewén; Lars Hillered; Niklas Marklund; Anders Lewén; Mårten Risling; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Astrocytes; Inflammatory response; Multivariate concentric square field test; Morris water maze; Exploratory behavior; Risk taking; Functional outcome.; Neurosurgery; Neurokirurgi;

   Abstract : Traumatic brain injury (TBI) is a severe condition and a major cause of death and disability. There is no pharmacological treatment available in clinical practice today and knowledge of brain injury mechanisms is of importance for development of neuroprotective drugs. READ MORE

5. 3. Cerebral ischemia studied with positron emission tomography and microdialysis

   Author : Peter Frykholm; Peter Kirkpatrick; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cerebral ischemia; penumbra; positron emission tomography; microdialysis; middle cerebral artery occlusion; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

   Abstract : Stroke is the third leading cause of morbidity and mortality in the industrialized world. Subarachnoid hemorrhage (SAH), the least common form of stroke, is one of the most demanding diseases treated in neurointensive care units. Cerebral ischemia may develop rapidly, and has a major influence on outcome. READ MORE

6. 4. Deep brain stimulation of the posterior subthalamic area in the treatment of movement disorders

   Author : Anders Fytagoridis; Patric Blomstedt; Joachim Krauss; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Deep brain stimulation; Movement disorders; Posterior subthalamic area; Zona incerta; Prelemniscal radiations; Tremor; Essential tremor; Parkinson s disease; neurokirurgi; Neurosurgery;

   Abstract : Background: The posterior subthalamic area (PSA) is essentially composed of the caudal Zona incerta and the prelemniscal radiation. Subthalamotomy in the PSA was renowned for its effectiveness in alleviating movement disorders and particularly tremor. READ MORE

7. 5. Plasticity and Inflammation following Traumatic Brain Injury

   Author : Anders Hånell; Niklas Marklund; Lars Hillered; Nikolaus Plesnila; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic Brain Injury; plasticity; inflammation; Nogo receptor; EphA4; IL-1β; Neurosurgery; Neurokirurgi; Neuroscience; Neurovetenskap;

   Abstract : Traumatic Brain Injury (TBI) mainly affects young persons in traffic accidents and the elderly in fall accidents. Improvements in the clinical management have significantly improved the outcome following TBI but survivors still suffer from depression, memory problems, personality changes, epilepsy and fatigue. READ MORE