Search for dissertations about: "neurotrophins"

Showing result 11 - 15 of 56 swedish dissertations containing the word neurotrophins.

2. 11. Peripherally administered choleocystokinin-8 increases neurotrophins in the brain

   Author : Paola Tirassa; Karolinska Institutet; Karolinska Institutet; []
   Keywords : NGF; BDNF; CCK-8; glutamate; GABA; CCK receptors; hypothamalus; hippocampus; Choline Acetyltransferase; fimibria-fornix transection; vagotomy; vagal stimulation; RT-PCR; ELISA;

   Abstract : The aim of this thesis was to test the hypothesis that the gastric hormone Cholecystokinin-8 (CCK-8) can modulate the production of Nerve Growth Factor (NGF) in the brain. NGF is the first discovered and the best characterized neurotrophic factor which plays a crucial role in the survival and development of basal forebrain cholinergic neurons (BFCN). READ MORE

4. 12. Effects of neonatal handling and enriched environment on neurotrophins and cognitive function

   Author : Therese M Pham; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Postnatal handling; Postnatal nonhandling; Enriched environment; Isolated environment; Neurotrophins; Behaviour; Rat;

   Abstract : Environmental stimulation plays a critical role in the development and maintenance of behaviours and neural processes. Two experimental models that have guided research on behavioural and neural plasticity are Postnatal handling and Environmental enrichment. READ MORE

5. 13. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia

   Author : Gunnar Andsberg; Lund Neurologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; Neurology; animal behaviour; striatum; stereology; immunohistochemistry; focal cerebral ischemia; nerve growth factors; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Abstract : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. READ MORE

6. 14. Biochemical and biophysical aspects of molecular recognition and signalling by neurotrophins

   Author : Leopold Luna Ilag; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Neurotrophins are members of a family of structurally and functionally related neurotrophic factors that control the development and maintenance of the nervous system. There are currently 5 members which make up this family: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4(NT-4) and neurotrophin-6 (NT-6), which so far is only described in fish. READ MORE

7. 15. Regulation of neurotrophins and their receptors : molecular aspects and functional implications

   Author : Tuija Salin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : neurotrophin; nerve growth factor; brain-derived neurotrophic factor; neurotrophin-3; neurotrophin-4; glia; gliosis; neuron; tyrosine kinase receptor; transgenic; null mutation; gene; exon; intron; mRNA;

   Abstract : The aim of this work was to study the regulation of neurotrophins and their receptors in a functional aspect. The studies included analysis of neuronal and glial neurotrophin gene expression, that was investigated by using molecular biological techniques. READ MORE