Search for dissertations about: "neutralizing antibodies"
Showing result 1 - 5 of 110 swedish dissertations containing the words neutralizing antibodies.
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1. Effects of galectins and antibodies in HIV infection; Novel Assays
Abstract : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. READ MORE
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2. Immunological characteristics of recombinant fragments of the Plasmodium falciparum blood-stage antigen Pf332
Abstract : Effective malaria vaccine might help improve control strategies against malaria, but the complexity of interactions between the parasite and its hosts poses challenges. The asexual blood stage P. falciparum antigen Pf332 has potentials as one of the proteins in understanding the complex host-parasite interactions. READ MORE
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3. Interferon-beta treatment in multiple sclerosis : analysis of neutralizing antibodies
Abstract : Multiple sclerosis (MS) is a disabling chronic neurological disease with a significant impact on patients lives. There is no cure for MS, but recombinant interferon beta (IFN-beta) is currently the most established disease modifying therapy. READ MORE
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4. Evaluation of new strategies to elicit neutralizing antibodies against HIV-1
Abstract : The development of an effective HIV-1 vaccine must be considered one of the greatest biomedical challenges of today. The nature of the virus, characterized by immense variability as well as its tropism for the essential CD4+ T cells of the immune system, allows it to establish a chronic infection for years under constant immune selection pressure. READ MORE
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5. Studies on Potency and breadth of HIV-1, HIV-2 and SIV neutralizing antibody responses
Abstract : Even though the relative contribution of neutralizing antibodies (Nab) to prevent progression to AIDS during HIV-1 infection is still unclear, the induction of broadly NAb directed against HIV-1 through vaccination is considered to represent an important goal for the development of HIV-1 vaccines. Factors contributing to the induction of NAb may include the strength and duration of antigenic stimulation, the preservation of CD4+ T and B cells, the conformation of the HIV-1 envelope glycoprotein complex (Env), and the evolution of Env during infection. READ MORE