Search for dissertations about: "neutrophil extracellular traps"

Showing result 16 - 20 of 31 swedish dissertations containing the words neutrophil extracellular traps.

  2. 16. The Impact of Tryptase and Epigenetic Mechanisms on Mast Cells

    Author : Sultan Alanazi; Gunnar Pejler; Constantin Urban; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mast cells; mastocytosis; tryptase; histone; DNA; methylation; neutrophil extracellular traps; Immunologi; Immunology;

    Abstract : Mast cells have a large influence on multiple immune-mediated responses, including allergic conditions, and they have been implicated in various diseases such as arthritis and cancer. Mastocytosis is characterized by abnormal mast cell proliferation induced by mutations in KIT, the stem cell factor (SCF) receptor. READ MORE

  4. 17. Modulation of neutrophil extracellular trap formation in health and disease

    Author : Ava Hosseinzadeh; Constantin F. Urban; Carol Munro; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Candida albicans; Adenosine; Tempol; Nicotine; molekylärbiologi; Molecular Biology;

    Abstract : The critical prompt innate immune response is highly built upon the influx of neutrophils from the blood stream to the site of infection. In the battlefield, neutrophils sense pathogen-associated molecular patterns (PAMPs) through their pattern-recognition receptors (PRRs) to launch a number of responses with the goal to defeat the invading pathogen. READ MORE

  5. 18. Insights into the processes preceding the onset of rheumatoid arthritis

    Author : Linda Johansson; Solbritt Rantapää Dahlqvist; Mikael Brink; Felipe Andrade; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; pre-symptomatic individuals; autoantibodies; anti-citrullinated protein peptides antibodies; Epstein-barr virus; neutrophil extracellular traps; periodontitis; Porphyromonas gingivalis; receptor activator of nuclear factor kappa-B ligand; reumatologi; rheumatology;

    Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by the production of anti-citrullinated protein antibodies (ACPA) in the majority of all patients and a persistent inflammation in the synovial tissue leading to joint destruction. The aetiology of RA remains to a large extent unknown but is believed to be a complex interplay between genetic, environmental and stochastic factors. READ MORE

  6. 19. Troponin elevation in acute stroke : clinical characteristics and the link to cancer-associated neutrophil extracellular traps

    Author : Charlotte Thålin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Elevated plasma levels of troponin, a marker of myocardial injury, are a frequent observation in stroke patients. Despite several reports on an adverse short-term prognosis, however, the significance of troponin elevation in stroke is still controversial, and the myocardial injury often lacks a clear etiology. READ MORE

  7. 20. Unraveling the immune response in sepsis and meningitis. Diagnostic and therapeutic approaches

    Author : Jane Fisher; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; meningtis; sepsis; neutrophil extracellular traps NETs ; glymphatic system; DNase; pneumococci;

    Abstract : Severe infections continue to constitute a large burden, with high mortality and risk of sequelae. Sepsis is a dysregulated host response to an infection that causes life threatening organ damage. Meningitis is a severe infection of the brain that often leads to sepsis and death or lasting neurological damage. READ MORE